Gastric cancer Flashcards

1
Q

Define gastric cancer

A

Tumour in any part of the stomach-usually adenocarcinomas

can be diffuse or intestinal (diffuse is all over-worse prognosis)

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2
Q

Aetiology and risk factors of gastric cancer

A

Few genetic components (HER2/neu), but mainly environmental agression-
HPV, smoked foods, salted foods

Risk factors- 
Stomach ulcers (HPV)
Age,
Being non caucasian
Perinicous aneamia
Male
Smoking
FHx
Low fruit/veggie diet
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3
Q

Epidiemology of gastric cancer

A

Much higher in SEA, Eastern Europe

about 10 per 100000 in UK
decline in western world (mainly US)

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4
Q

Signs and Sx of gastric cancer

A
Vague abdo pain-usually epigastric
FLAWS
Weight loss (most common PC)

Raised virchows node
Nausea, Dysphagia
20% present with Malena

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5
Q

Investigations for Gastric cancer

A

Endoscopy-any suspected gastric cancer should have a OGD + biopsy
HPV test
Endoscopic ultrasound determines staging
CT/XRAy- metastasis

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