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Pharm 1 > Gasses > Flashcards

Gasses Flashcards

1
Q

Loss of chest wall stability

A

Halothane

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2
Q

Decreases seizure threshold

A

Enflurane

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3
Q

Order of increased CBF

A

Halo>Enf>Iso=Des

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4
Q

Decrease in BP due to Decreased myocardial contractility

A

Halothane

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5
Q

order of decreased SVR greatest to least

A

Iso>des>sevo

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6
Q

Order of cardiac stimulation

A

Des>iso>sevo

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7
Q

Order of coronary vasodilation

A

Iso>des>sevo

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8
Q

Order for CMRO2

A

Iso=des=sevo>Halo

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9
Q

Dose depended decreased in CO

A

halothane

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10
Q

Order for hepatic effects

A

Halo>Enf>Iso>Des (no sevo)

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11
Q

Order for carbon monoxide toxicity

A

Des>Enf>Iso
(halothane and sevo do not)

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12
Q

What gas increases motor activity

A

N2O

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13
Q

Which 3 gases suppress convulsant properties

A

Sevo, Iso, Des

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14
Q

Fast frequency and high voltage on EEG indistinguishable from changes produced by seizure activity

A

Enflurane

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15
Q

Intrinsic dose dependen cerebral vasodilatory effect, but this effect is less than that of iso

A

Sevo

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16
Q

Twitching of facial and extremity muscles occurs

A

Enflurane

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17
Q

Which gas has the least effect on increased ICP (it still increases it but not as much as the other gases)

A

N2O

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18
Q

No change in BP or modest increased when given alone

A

N2O

19
Q

Order for Heart rate

A

Des>iso>sevo

20
Q

Depresses carotid sinus

A

N20

21
Q

what has no change in HR

A

Halothane

22
Q

Which gas increases Cardiac output

A

N2O

23
Q

Which gas causes dose dependent decrease in cardiac output

A

sevo (up to 2 MAC then recovers)

24
Q

Which gas decreases cardiac output

A

Halothane

25
Q

All gases decrease what Stroke volume

A

Left

26
Q

What two gases have no change in SVR

A

halothane and N2O

27
Q

What gas increases PVR exaggerated in PHTN, neonates, congenital heart dx

A

N2O

28
Q

What gases decrease PVR

A

Sevo, iso, des (des at MAC 1.6)

29
Q

which two gases transiently increase ALT

A

Enflurane and Desflurane

30
Q

at a MAC of what causes vasodilation of hepatic circulation (increased proton vein blood flow) for isoflurane

A

1.5

31
Q

what 3 gases are at risk for causing hepatoxicity

A

Iso, des and enflurane

32
Q

What gas causes possible rigidity in a hyperbaric chamber

A

N2O

33
Q

what is the most potent trigger for MH

A

halothane

34
Q

what 3 gases cause skeletal muscle relaxation

A

sevo, iso, des

35
Q

what effect do all volatile anesthetics cause to the kidneys

A

decreases renal blood flow
decreased GFR
decreased urine output

36
Q

vinyl halide nephrotoxicity from what gas react with CO2 absorbents. What can you do to reduce this

A

sevo
need 2L/min for FGF to minimize compound A

37
Q

what gas has very little metabolism- mainly by anaerobic bacteria in GI tract

A

N2O

38
Q

3% metabolized by cytochrome P-450

oxidative metabolism

A

Enflurane

39
Q

15-20% metabolized by cytochrome P-450

oxidative metabolism

A

halothane

40
Q

0.02% metabolized by cytochrome P-450

oxidative metabolism

A

Des

41
Q

0.2% metabolized by cytochrome P-450

oxidative metabolism

A

Iso

42
Q

5% metabolized by cytochrome P-450

oxidative metabolism

A

Sevo

43
Q

what gas degrades by CO2 absorbents to compound A

A

sevo

44
Q

Coronary blood flow

A

Halo, Enf<Iso<Adenosine

Pharm 1 (3 decks)

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