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Primary > Gases > Flashcards

Gases Flashcards

1
Q

What is the MAC of N2O
What is the oil:gas coefficient of N2O

A

the MAC of N2O is 104
the oil:gas coefficient of N2O is 1.4

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2
Q

What is the MAC of Sevoflurane

A

Sevo MAC: 2%

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3
Q

What is the MAC of halothane

A

0.75

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4
Q

What is the MAC of Isoflurane

A

1.2

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5
Q

What is the MAC of Enflurane

A

1.6

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6
Q

What is the MAC of Desflurane

A

6

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7
Q

what is oil:gas coefficient

A

measure of conc in oil/conc in gas.
key indicator of lipid solubility which correlates to potency. Higher the oil:gas, the lower the MAC because less will be needed (i.e more potent)

This relationship is explained by the Meyer-Overton hypothesis, which states that the potency of an anesthetic is directly related to its ability to dissolve in the lipid bilayer of neurons.

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8
Q

what is the oil:gas coefficient of sevo

What percentage of sevo is metabolised

A

oil:gas coefficient of sevo is 47 -53(sources vary)

3-5% metabolised in liver

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9
Q

what is the oil:gas coefficient of Halothane

A

224

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10
Q

what is the oil:gas coefficient of desflurane

A

18.7

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11
Q

which anaesthetic gas has a pungent smell and can irritate airways?

A

desflurane has a pungent smell and can irritate airways (unlike halothane)

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12
Q

what is boiling point of desflurane?
What is it heated to in a TEC 6 vapouriser?

A

Des BP- 22.8 degrees celcius
TEC 6 vapouriser heats Des to 39 degrees celcius

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13
Q

what is blood: gas coefficient?

A

ratio of anaesthetic in blood compared to inspired air in alveoli when the system reaches equilibrium

low blood:gas coefficient= fast onset and faster recovery.
e.g Des has a low blood:gas coefficient and a faster onset of anaesthesia
It determines onset and offset time. Higher blood:gas coefficient means

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14
Q

what is blood:gas coefficient of Desflurane

A

0.42 (rapid)

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15
Q

what is blood:gas coefficient of sevo

A

0.69 (moderate onset/offset)

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16
Q

what is blood:gas coefficient of Isoflurane

A

1.4 (slow onset/offset)

17
Q

what is blood:gas coefficient of Halothane

A

2.4 (slow onset ^ recovery)

18
Q

what is the boiling point of halothane ?

A

50.2 degrees celcius

19
Q

What is the alveolar gas equation for working out alveolar oxygen tension (PAO2)

A

PAO2=[FiO2 x(Patm-PaH2O)]/ R

Where R is respiratory quotient (amount of CO2 produced (200ml/min) divided by amount of O2 consumed (250ml/min).
The value with a normal diet is 0.8
PAO2= PiO2 - PaCO2/ R
PiO2 = FiO2 - (PB-PaH2O)
e.g 0.21- (100kPa -6.3kPA)
because partial pressure exerted by water vapour at body temp is around 6.3kPa

Primary (31 decks)

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