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Anesthesia secrets > gases > Flashcards

gases Flashcards

1
Q

Sevo MAC

A

1.8

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2
Q

Des VP

A

669

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3
Q

Sevo VP

A

160

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4
Q

Nitrous oxide VP

A

39,000

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5
Q

Iso BGC

A

1.46

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6
Q

Des BGC

A

0.42

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7
Q

No BGC

A

0.46

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8
Q

Sevo BGC

A

0.69

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9
Q

Factors that increase speed of induction

A

low BGC (low solubility of agents), decreased CO, increasing delievered concentration,

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10
Q

VAAs effects on ventilation

A

depresses ventilation mediated directly through medullary centers and indirectly through intercostal muscle function, RR tends to increase, TV tends to decrease …. drive to breath from hypoxia abolished at 1 MAC

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11
Q

VAAs effect on airway resistance

A
  • decrease airway resistance by relaxing bronchial smooth muscle
    NOTE: VAAs are potent vasodilators
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12
Q

VAAs effect on hypoxic pulmonary vasoconstriction

A

reduce effect of HPV

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13
Q

VAAs effect on brain

A

increase CBF and ICP
CMRO2 decreased (except for N2O) and autoregulation is impaired

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14
Q

VAAs effect on renal system

A

decrease RBF, GFR, and UOP

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15
Q

How are VAAs metabolized

A

des and iso metabolized less tha 1%

Sevo metabolized around 5%

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16
Q

ISOs effect on CO, HR, BP, SVR, PVR, coronary blood flow

A

no change
large increase to no change
large decrease to no change
large decrease
no change
increase

17
Q

Sevos effect on CO, HR, BP, SVR, PVR, coronary blood flow

A

No change
no change
large decrease to no change
large decrease
no change
increase

18
Q

N2O effect on CO, HR, BP, SVR, PVR, coronary blood flow

A

increase
increase
no change
no change
increase
no change

19
Q

Des effects on HR, BP, CO and SVR

A

Increase, Decrease, decrease to no change, decrease

20
Q

VAAs mechanism of action

A
  1. stimulate inhibitory receptors
    • in the brain… VAAs increase amount of time GABA-A channels are open
  2. Inhibit stimulatory receptors
    - in the spinal cord… will produce immobility in ventral horn. site of action= glycine (stimulation), NMDA- glutamate (inhibition) and Na channel (inhibition)
21
Q

Which VAA worsens bronchospam? whats the best choice for bronchospasm risk?

A

Des, Sevo

22
Q

When should you avoid N2O?

A

inner ear, intraocular, pneumo… avoid in pregnancy and B12 deficiency

NOTE: does add analgesic properties

23
Q

Why should you not overpressurize Des?

A

SNS stimulation

24
Q

Des MAC

A

6.6

25
Q

Iso MAC

A

1.17

26
Q

NO MAC

A

104

27
Q

Iso VP

A

238

Anesthesia secrets (5 decks)

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