gas exchange Flashcards

1
Q

Where does gaseous exchange occur

A

Between alveoli and capillaries

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2
Q

What’s the level of Nitrogen measurable in dry air/alveolar air

A

79% Dry air

75% Alveolar air

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3
Q

What’s the level of Oxygen i’m dry air/alveolar air

A

21% Dry air

14% Alveolar air

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4
Q

What’s the level of carbon dioxide in dry air/alveolar air

A
  1. 04% Dry air

5. 3% alveolar air

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5
Q

What is the level of water vapour in Dry air/alveolar air

A

0 Dry air

6.2% alveolar air

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6
Q

What are the 2 types of cells lining the alveoli

A

Numocytes

Type 1 help with gas exchange
Type 2 store and secrete surfactant

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7
Q

What is haemoglobin made of

A

4 Globins (polypeptide chains)
4 Haem molecules
carry’s 98% of oxygen

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8
Q

Which is more soluble in water, oxygen or carbon dioxide?

A

Carbon dioxide

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9
Q

When is haemoglobin’s affinity with oxygen highest

A

After 1 haem molecules has bound with 1 oxygen molecule this changes the overall shape increasing its affinity with oxygen

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10
Q

What is the % of saturation when the partial pressure of oxygen is 80mmHg?

A

95.8%

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11
Q

What are the forms of transport of carbon dioxide

A

70% HCO3 Bicarbonate ions
23% haemoglobin
7% dissolved in plasma

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12
Q

How is carbon dioxide bonded with haemoglobin

A

CO2HB Carbino haemoglobin

Binds with the globin aspect

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13
Q

How is 70% carbon dioxide absorbed

A

Carbon dioxide binds with water to form carbonic acid. This process is assisted by the enzyme carbonic anhydrase.
This splits into hydrogen ions and bicarbonate ions which then leave the red blood cell body.

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14
Q

How is the ionic composition of the red blood cell maintained during absorption of carbon dioxide

A

Chloride shift - chloride ions with negative charge diffuse into the cell body

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15
Q

What happens when there is a right shift of the oxygen disassociation curve?

A

Reduced affinity with oxygen less oxygen is absorbed. This could be due to increased temperature, increased hydrogen ions ( if the level of carbon dioxide increases in blood cell)
This could be due to exercise

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16
Q

Value of oxygen in blood

Co2 in blood

O2 saturation

A

11-14 kpa 80-100mmhg

4-6 kpa 35-45 mmhg

98%

17
Q

What is the Bohr shift

A

Due to increased hydrogen ions in the red blood cells haemaglobin decreases its affinity with oxygen to enable it to transport more co2 out of the body

Can be due to increased temp, exercise etc.

18
Q

What is a right shift in a disassociation curve

A

Increased affinity to oxygen

Foetal haemoglobin

19
Q

Stretch receptors

A

I thin smooth muscle bronchial walls — communicate to vague nerve — Dorsal respiratory group — makes inspiration shallower and shorter prevents the lungs over stretching

20
Q

Juxtapulmonary receptors

A

Within alveoli and bronchial walls — vagus nerve — Dorsal respiratory group — Apneoa or shallower breathing

21
Q

Proprioreceptors

A

Position/length receptors in respiratory muscles (not diaphragm)

22
Q

Do2

A

Delivery of oxygen

23
Q

Vo2

A

Oxygen consumption