Gas Exchange (4) Flashcards
How do ideal gas law apply to respiratory gas exchange?
Ideal gases do NOT condense, evaporate, or sublime at operating range
- O2 and CO2 are Ideal cases at operating ranges
- Ideal gases follow PV=nRT formula
- since temp. between the inspired air and the body are similar due to warming and humidification, PO2 + VO2 = PCO2 +VCO2
- Since there is a partial pressure difference, diffusion occurs both ways until equilibrium
how does ATELECTASIS affect gas exchange
- Change in pressure is DECREASED (alveolar PO2 is decreased), resulting in decreased diffusion
How does PULMONARY FIBROSIS affect gas exchange
distance of diffusion increases (interstitial thickness), resulting in decreased diffusion
How does PULMONARY EDEMA affect gas exchange
Distance of diffusion increases (fluid in interstitium), resulting in decreased diffusion
How does PNEUMONIA affect gas exchange
Distance of diffusion increases (inflammation of alveoli), resulting in decreased diffusion
define the relationship between diffusion and perfusion in the effectiveness of gas exchange in lungs
Both proper ventilation and perfusion are necessary to establish the appropriate partial pressure difference for diffusion to occur properly
Describe the process of O2 exchange at alveoli-pulmonary capillaries under normal conditions and during strenuous exercise
NORMAL: blood passes through capillaries, blood PO2 is almost fully saturated after traveling 1/3 distance of capillary.
EXERCISE: 20x the amount of O2 can be needed, CO increases, which reduces the amount of time the blood spends in capillaries
- diffusion capacity increases in excercise, so blood is almost saturated before leaving capillary