Gamma Knife Flashcards

1
Q

What are the 4 main features of radiosurgery?

A
  • single high dose (12-150Gy)
  • tissue ablation/destruction
  • requires defined target
  • typically for targets less than 3-4cm
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2
Q

What lesions are treated with GK?

A
  • meningioma
  • brain mets
  • trigeminal neuralgia
  • acoutis neuromas
  • arteriovenous malformations
  • pituitary lesions
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3
Q

What are the clinical indications for meningioma GK?

A
  • slow growing
  • dose is 12-20Gy
  • control rate 90% at 5yrs
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4
Q

What are the clinical indications for brain mets GK?

A
  • avoid complications with WBRT
  • improved QOL
  • dose 15-22Gy
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5
Q

What are the clinical indications for trigeminal neuralgia GK?

A
  • most severe pain syndromes
  • medical management fails patients require surgical intervention
  • GK less invasive usually older patients
  • dose 75-90Gy
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6
Q

What are the clinical indications for acoustic neuromas GK?

A
  • slow growing, benign usually from vistibular portion of 8th nerve
  • unilateral hearing decline
  • dose 12-13Gy
  • 93-100% control
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7
Q

What are the clinical indications for ateriovenous malformations GK?

A
  • goal is complete obliteration
  • reduce lifetime risk of hemorhage to 1% or less
  • dose 18Gy in 1#
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8
Q

What are the clinical indications for pituatary lesions GK?

A
  • good for reccurent or residual nonfunctional pituitary adenomas
  • GK high tumour control and reasonable rate of endocrine remission in patients with Cushing’s disease
  • dose 15-26Gy
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9
Q

What are some features of a GK bunker?

A
  • staff swipe access in and out of patient waiting and maxe door
  • after treatment hrs area past maze dorr is alarmed and locked by key
  • treatment door locked when not in use
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10
Q

What is the MDT workflow for GK?

A
  • statewide servie
  • MDT team (neursurgeons, RO, RT, physcisits, nurses, MI and allied health)
  • weely MDT meeting
  • weekly MDT clinic
  • treatment day
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11
Q

What happens on treatment day for single fraction patients?

A
  • frame attachment
  • planning CT
  • planning MRI
  • treatment plan
  • QA
  • treatment
  • frame removal
  • discharge
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12
Q

What does the radiation unit include for GK?

A
  • collimator system
  • 192 60 Cobalt sources
  • two gamma rays (1.17 Mev, 1.33 MeV)
  • shielding
  • shielding doors
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13
Q

What is the half like of 60Co and how often does it need changing?

A
  • 5.25 yr half life

- change every 5 years

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14
Q

What is the imaging process?

A
  • frame provide spacial references and immbolises the patients head
  • patient scanned with an indicator box in place
  • reference fiducials during image acquisition
  • creates the stereotactice space for each image
  • images sent directly to gamma plan via dicom
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15
Q

How does gamma plan define images?

A
  • fiducial markers are defined for each image imported into gamma plan
  • creates the sterotactic space
  • leksell coordinates on the image for placing treatmen shots
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16
Q

What are the planning goals for GK?

A
  • conformity
  • gradient (steep dose fall off)
  • coverage
  • selectiviy (how much PTV is inside the TV)
  • CI
17
Q

What are some common features of GK treatment?

A
  • can’t proceed while issues are displayed
  • treatment time 8 min to 2hr
  • pause options e.g toilet break
  • during treatment patients; fall asleep, listen to music, relax
  • microphone communication
18
Q

What are some benefits of GK?

A
  • improved patient QOL
  • minimally invasive compared to surgery
  • eliminates risks associated ith GA
  • decreased risk of hearing loss, facial weakness and balance problems for acoustic neuroma patients
  • decrease dose to NTT thus decreased impact on neurocognitive effects
19
Q

What are some challenges associated with GK?

A
  • uses live radiation source so need tight security
  • additional staff training
  • only be used for brain lesions