game Flashcards
(37 cards)
What are lymph nodes?
Mass of lymphoid tissue
What is Lymph?
excess tissue fluid
Where are Lymph nodes located?
along lymphatic vessels
What do lymph nodes contain?
lymphocytes and macrophages
What are lymph nodes covered with?
connective tissue
What is the function of lymph nodes?
filter debris from intracellular spaces
What is the thymus?
A soft, bilobed gland located in the mediastinum anterior to the aortic arch
What does the thymus secrete?
Hormone: Thymosin
What is the largest organ of the lymphatic system?
spleen
What is the spleen?
Resembles a large lymph node except it contains blood instead of lymph
what is something that is not true about the NK cells?
NK cells are a type of neutrophil.
Phagocyte mobilization involves ________.
mainly neutrophil and macrophage migration into inflamed areas
List the functions of macrophages
Phagocytosis
- Ag presentation
- Secretion (cytokines)
- Migration
Natural killer (NK) cells ________.
can kill cancer cells before the immune system is activated
What stimulates natural killer cells?
NK cells are either activated by immunoreceptor tyrosine-based activation motifs (ITAMs)
How many natural killer cells are made each day
6 and 25
Recruited monocyte-derived macrophages are often____
F4/80low
3 of the 5 of the White blood Cells; neutrophils, eosinophils,
and basophils are called-
Granulocytes
Resident macrophages are often _____
F4/80 high
What are regulatory T-Cells?
Regulatory T cells (also called suppressor T cells) suppress the response of B cells and other T cells to antigens
What are helper T-Cells?
Helper T cells precipitate the production of antibodies by B cells and also produce substances that activate other T cells.
Without the positive selection process in lymphocyte maturation ________.
T-cells would not be able to properly bind to APC’s and therefore not be activated by them.
Lymphocytes Develop Immunocompetence in the:
bone marrow
What does MHC stand for?
Major Histocompatibility Complex
