Gallbladder Cancer

Question 1

What percentage of cholecystectomy specimens are found to have gallbaldder carcinoma?

Answer 1

1%

Question 2

Based on published data, what is the 5-year survival of patients who undergo R0 resection for gallbladder carcinoma?

Answer 2

16.50%

Question 3

What are the most common sites of metastases from gallbladder carcinoma?

Answer 3

noncontinguous liver mets (91%), lung (32%), brain (5%)

Question 4

What is the incidence of lymph node metastases in T2 or greater lesions?

Answer 4

50%

Question 5

What is the appropriate surgical management of patients with T1 dusease?

Answer 5

simple cholecystectomy

Question 6

What is the appropriate surgical management of patients with T2 dusease?

Answer 6

radical cholecystectomy + regional lymph node dissection (periportal, peripancreatic, and celiac nodes)

Question 7

What are the recommendations for adjuvant radiation and chemotherapy?

Answer 7

XRT in node-positive disease and chemotherapy as a radiation-sensitizing agent following resection

Question 8

What is the median survival for unresectable gallbladder carcinoma?

Answer 8

2-4 months