Gallbladder And Pancreas Flashcards

1
Q

Asymptomatic gallstones do not require treatment except if?

A

Large stones > 3cm

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2
Q

What is the gold standard test for acute cholecystitis

A

HIDA- if positive the gallbladder wont be visualized

In Advance liver failure HIDA scan will be false positive because liver is not functioning so the gall bladder is not visualized

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3
Q

What is Mirizzi’s syndrome

A

Present with Dilated common hepatic duct and Jaundice

This is a complication of cholecystitis due to impacted stone in the cystic duct/gall bladder neck —-> the stone compresses the hepatic duct—> this results in obstruction and jaundice

Ultrasound shows gallstone and dilated common hepatic duct

Treatment is surgical cholecystectomy

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4
Q

What is a choledochoduodenal fistula AKA Cholecystoenteric fistula?

A

Erosions of gallstones through the gallbladder wall, so the gallstone erodes through the wall into the duodenum, from there the stone can travel down and cause obstruction at the terminal ileum and ileocecal valve

High mortality requiring urgent cholecystectomy or urgent cholecytostomy

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5
Q

What is chronic a calculus cholecystopathy (AKA Gallbladder dyskinesia) and how is it Dx and treated?

A

There is decrease gallbladder emptying leading to gallbladder dyskinesia, this causes RUQ pain

Patient have symptoms of biliary coli with NL U/S we can Dx with Radionucleotide scintigraphy with the CCK-stimulated gallbladder ejection fraction (+ is <35%)

Treatment is cholecystectomy

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6
Q

What does U/S shows in Acute Acalculous cholecystitis

A

Large, tense, static gallbladder without stones with evidence of poor emptying

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7
Q

What is choledocholithiasis and what is its most feared complications

A

Stone in the CBD

cholangitis

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8
Q

What is charcot’s Triad for Cholangitis?

A

RUQ pain
Fever
Jaundice

Raynaud’s
+ Hypotension, AMS

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9
Q

How do we workup a gallbladder polyp

A

On u/S gallbladder polyps do not move whereas stone do.

Gallbladder polyps more than 10 mm are more likely malignant and are usually adenocarcinoma.

Findings of a gallbladder polyp warrants cholecystectomy

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10
Q

what is cholangiocarcinoma?

How does patient present?

A

this is a bile duct cancer. When it is located near the porta hepatic it is called Klatskin tumors

Patient typically present with obstructive jaundice

Courvoisier sign: Distended palpable gallbladder

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11
Q

How does Adenocarcinoma of the Ampulla of Vater present?

What kind of patients do we typically see this in?

A

The ampulla of Vater is in the duodenum, this cancer because it is located in the duodenum can present with a UGIB (Melaka, iron def anemia).

Also because its in the ampulla it can cause obstructive jaundice

Typically seen in patients with :

  • FAP, especially Gardener syndrome
  • Peutz-Jeghers
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12
Q

According to the revised Atlanta classification of pancreatitis what are the 2 types?

What are the 2 phases of acute pancreatitis?

How is severity classified?

A
  1. Interstitial edematous pancreatitis (MC)
  2. Necrotizing pancreatitis

2 Phases
Early <1 week
Late phase after 1 week

Severity:
Mild=no organ dysfunction (Hypotension not responding to fluid, AKI, Respiratory Failure)
Moderate=Transient organ failure that resolves in <48 hours
Severe= Organ failure >48 hours

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13
Q

What are the local complications of acute pancreatitis?

A
  1. Interstitial edematous pancreatitis:
    <4 weeks=Acute peripancreatic collection
    >4 weeks=Pseudocyst
  2. Necrotizing pancreatitis
    <4 weeks=Acute necrotic collection
    >4 weeks=Walled of necrosis
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14
Q

Which scoring system is used to predict mortality in acute pancreatitis?

A

BISAP score

BUN >24
Impaired mental ion
SIRS
Age >60
Pleural effusion
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15
Q

Patients with Gallstone pancreatitis undergoing cholecystectomy should also undergo what additional test and why?

A

They should undergo Lap chole with Intraoperative cholangiogram

The cholangiogram is done to see if there is any filling defects in the CBD for retained stone; if + then the patient will also need to undergo ERCP with stone extraction

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16
Q

Causes of death in pancreatitis?

A

First Week= Organ failure (ARDS, Shock)

After First Week=Pancreatic or systemic infections

17
Q

How do we diagnose Pancreatic necrosis?

A

If symptoms do not resolve after 72 hours order CT with contrast

Necrosis is usually sterile (chemical necrosis) but if infection is suspected (ie fever) FNA under CT guidance is performed

18
Q

What are other complications of acute pancreatitis?

A
  • Asymptomatic pancreatic or extra-pancreatic necrosis and pseudocyst need no intervention regardless of size, location, or extent
  • Symptomatic mature pseudocysts are drained
  • Pseudoaneurysm formation with bleeding into the retroperitoneum and bowel treatment is with embolization
  • Can lead to fistula formation
  • Splenic vein thrombosis-leads to isolated gastric varies
  • Alcoholic pancreatitis can lead to diabetes
19
Q

What test are ordered for chronic pancreatitis?

A

First test Fecal elastase/ chymotrypsin (low in chronic pancreatitis)

Serum trypsinogen

If all negative can do Secretin-CCK test

20
Q

what is the best initial imaging for chronic pancreatitis?

A

CT abdomen

21
Q

which immunoglobulin is elevated in Autoimmune pancreatitis?

A

IgG4

22
Q

What constitutes the majority of pancreatic cancers?

A

Adenocarcinoma makes 90%

Neuroendocrine tumors make 5% (Gastrinoma, Insulinoma, Glucagonoma, VIPoma, Somatostatinoma)

23
Q

Presentation of pancreatic cancer?

What is the workup?

A
Abdominal or back pain
Weight loss
Jaundice
New onset DM
Worsening of previously controlled DM

Order CT scan with thin cuts this is followed by EUS with FNA

24
Q

How should a asymptomatic pancreatic cyst be be managed?

A

If cyst has more than 2 high risk features then EUS with FNA

No high risk features then MRI in 1 year, if unchanged, repeat MRI every 2 years for a total of 5 years.

25
Q

chronic non-healing anal fissure can be treated with?

A

Lateral internal sphincterotomy or Botox injections

26
Q

What are the types of constipation?

A
  1. Slow transit (MC type)
    - the normal colonic transit time of <72 hours is increased up to 120 hours
    - Rx fiber, laxatives
  2. Dyssynergic defecation or evaluation disorders (AKA Pelvic floor dysfunction)
    -when the patient is ready to poop instead of the pelvic floor relaxing it instead contracts and patient often strains
    -Dx with Anorectal Manometry
    Rx: Biofeedback
  3. constipation predominant IBS
    - Pain is predominant, transit time and pelvic function normal.
27
Q

When do we perform colonic transit and pelvic floor dysfunction testing for constipation?

A

when there’s no response to standard therapy

28
Q

How is continuation treated?

A

Fiber and Fluid

If no relief start with a bulking agent (psyllium) then osmotic (lactulose, polyethylene glycol, sorbitol) then stimulants (bisacodyl, senna)

29
Q

What medications a re approved for chronic idiopathic constipation And constipation predominant IBS

A

Lubiprostone

Linaclotide

30
Q

What medication is approved for opioid induce constipation?

what medication is proved for post-op ileus due to bowel surgery?

A

Methylnaltrexone

Alvimopan

31
Q

What do we use to screen for Malnutrition inpatient?

A

MUST screening tool or Nutritional risk screening tool

32
Q

Does PEG tube placement improve outcome in advance dementia patients?

A

No, it does not recent ulcers and it increase risk of aspiration PNA

they are only placed if enteral feeding needs are greater than 4 weeks

33
Q

Patients with PEG tube how should residuals be managed?

A

Check residuals q 4hours for first 48 hours

If Residual > 250 add promotility

If Residual >500 hold tube feeding and reassess

Also elevate head of bed for all patients on Peg feeding

34
Q

What electrolyte abnormalities do we see with reseeding syndrome?

A
Hypophosphatemia
Hypokalemia
Hypomagnesemia 
Hypocalcemia
hyponatremia