Gait, Cerebellar function, and Movement Disorders Flashcards

1
Q

Destruction of what column leads to a positive Romberg sign?

A

Dorsal column - lack of proprioception is normally compensated for with vision.

When you remove vision, you are no longer able to balance

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2
Q

Destruction of what part of the CNS leads to inability to stand with feet together, even with eyes open?

A

Cerebellum- visual clues cannot compensate when the cerebellum is destroyed

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3
Q

Name 5 systems/components necessary for walking/standing up

A

Strength (UMN, LMN, NMJ, muscle)
Coordination (cerebellum)
Postural control (extrapyramidal system)
Memory/concept of walking

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4
Q

WHat is a hemiplegic gait?

A

When one half of the lower limbs are affected - the affected half is extended and swung/circumducted.

The ipsilateral arm is flexed at the elbow and wrist and there is decreased armswing

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5
Q

Where is hemiplegic gait commonly observed?

A

Stroke patients

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6
Q

What is a tabetic gait?

A

“Foot slapping” gait

Patient compensates for impaired sensation

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7
Q

What disorder might lead to a tabetic gait?

A

Neurosyphilis (tabes dorsalis) leading to a degeneration of the dorsal column pathway

Severe neuropathy

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8
Q

What is a “steppage” gait?

A

Super high hip flexion to overcome weak dorsiflexion (foot drop)

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9
Q

What disease process causes a steppage gait?

A

Peroneal nerve or L5 root lesions

Severe neuropathy

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10
Q

What is a waddling gait?

A

when walking, weak pelvic or hip muscles cannot support the body “on one leg” while the opposite foot is lifted off the ground;

patient compensates by swaying or leaning to the left when the right foot is raised and vice versa, alternately tilting the pelvis from side to side, reminiscent of a waddling duck

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11
Q

What disease process causes a waddling gait?

A

Usually a myopathy

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12
Q

What causes a scissors gait?

A

Corticospinal tract lesions affecting the legs (spastic paralysis)

-Cerebral palsy or multiple sclerosis

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13
Q

Describe the Parkinsonian Gait

A

Slow, shuffling gait with “stooped forward” position and lack of normal arm swing

Turning around is slow and requires many small steps

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14
Q

What is the function of the cerebellum?

A

coordination and regulation of movement

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15
Q

What is a kinetic tremor?

A

rhythmic oscillations during limb movement towards a target

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16
Q

What is dysmetria?

A

overshooting or undershooting a target

17
Q

What is decomposition of movement?

A

a normally smooth movement becomes jerky, “broken down”

18
Q

What is the loss of check response (rebound)?

A

sudden release of contracted biceps leads to striking the face; triceps does not normally “check” (protect) this action due to imbalance of agonist/antagonist muscle

19
Q

Differentiate cerebellar hemispheral vs vermal syndromes

A

Hemispheral: affects ipsilateral limbs
Vermal: predominantly affects the trunk

20
Q

Alcohol predominately affects which part of the cerebellum?

A

The anterior superior vermis –> gait ataxia and lower limb dysmetria

21
Q

Which is the most common spinocerebellar degenerative disease?

A

Freiderich’s Ataxia

22
Q

Resting tremors are typical of what disease process?

A

Parkinson’s disease

23
Q

Postural tremors are typical of what disease process?

A

Familial essential tremor

24
Q

Kinetic tremors are typical of what disease process?

A

Cerebellar disease

25
WHat types of medications can lead to choreoathetosis or dystonia
High levels of dopaminergic medications
26
What is hemiballismus?
Rapid, violent ("ballistic"), flinging movements of proximal upper and lower limbs on one side
27
What is the cause of hemiballismus?
A lesion (usually infarction) of the contralateral subthalamic nucleus
28
What is dystonia?
Continual or sustained painful contractions of muscles causing turning and spasms of the limbs or neck, with fixed, unnatural posture Can be focal or generalized
29
What causes dystonia?
No specific lesion or disorder has been correlated with this disorder
30
What is tourettes syndrome?
INherited with variable penetrance- motor and vocal tics, more often in boys, associated with ADD and behavioral problems
31
What is myoclonus?
Rapid, shock like movements of the limbs or body, usually bilateral, but often asynchronous
32
WHat types of disorders cause myoclonus?
Diffuse encephalopathies from either neurologic (Creutzfeld-Jakob disease) or medical disease (renal or hepatic failure, anoxia)
33
What causes asterixis?
Seen bilaterally in medical diseases (renal or hepatic failure) Seen unilaterally in structural brain lesions
34
Name three pharmacologic agents used in the treatment of parkinsonian resting tremors
L-Dopa, anticholinergics and dopamine agonists
35
Name two pharmacologic agents used in the treatment of essential (kinetic) tremors
Beta-adrenergic blockers | Barbituates
36
Name a pharmacologic agent used in the treatment of choreoathetosis, hemiballismus and tics
Dopamine antagonists
37
Name three pharmacologic agents used in the treatment of dystonia
Anticholinergics, benzodiazepines, and Botulinum toxin