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Top 200 Drugs > GABA-A receptor activation > Flashcards

GABA-A receptor activation Flashcards

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1

Q

Topamax-Topiramate

A

Partial seizure, tonic-clonic seizures, migraine prevention

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Top 200 Drugs (120 decks)

Selective Beta-1 Blocker

SSRI(Selective Serotonin Reuptake Inhibitor)

Statin (HMG CoA Reductase Inhibitor)

CCB (Calcium Channel Blocker)

Biguanide antidiabetic

NSAID (Nonsteroidal Anti-inflammatory Drug)

Diuretic Combination

GABA-A Receptor Modulator

PPI (Proton Pump Inhibitor)

H1-Receptor Antagonist

Leukotriene Receptor Antagonist

COX-2 specific NSAID

T4 thyroid hormone

TCA( Tricyclic Antidressant

ADP-Inhibitor(Adenosine Diphosphate Inhibitor)

5HT&NE RI, weak DA RI(Serotonin & Norephinephrine & Dopamine Reuptake Inhibitor)

Long acting Beta-2 Agonist & Anti-inflammatory Corticosteroid

Vitamin K-Dependent Factors & Protein C, S Synthesis Inhibitor

CNS COX-1&2-Inhibitor/Weak u-Opiate Receptor Agonist

GABA Analog, MOA unkown

Anti-inflammatory Corticosteroid

H2-Antagonist(Histamine 2 Receptor Antagonist)

ACE-Inhibitor (Angiotensin Converting Enzyme Inhibitor)

PDE5 Inhibitor (Phosphodiesterase 5 Inhibitor)

Central action at the brain stem, reduction of tonic somatic motor activity influencing alpha and gamma motorneurons

ARB (Angiotensin Receptor Blocker)

CCB/ACE-Inhibitor Combination

u-Opiate Receptor Agonist/CNS COX-1&2-Inhibitor

u opioid-Receptor Agonist, 5HT&NE RI

Inhibit Ovulation

Central action in the spinal cord

Thiazolidinediones

Xanthine Oxidase Inhibitor

Alpha-2 Receptor Inhibitor

FQ(Fluoroquinolone)

DA Reuptake Inhibitor

Inhibits intestinal absorption of cholesterol

Vitamin supplement

Selective Alpha Receptor Blocker

5HT2 & DA-Receptor Antagonist

CNS stimulant through release of NE by binding to adrenergic receptors

CNS Stimulant through NE&DA RI

Potassium Sparing Diuretic;aldosterone receptor blocker

Digitalis glycosides, inhibit Na+/K+ ATPase

Sterol Inhibitor

Nonselective beta & alpha-1 Receptor Blocker

Beta-2 agonist/Anticholinergic combination

Inhibit ovulation through suppression of LH & FSH

Selective Alpha-1 Receptor Blocker

u-Opiate Receptor Agonist

Topic Corticosteroid

H-1 Receptor Antagonist/Decongestant

DA-Receptor Antagonist

GABA-A receptor activation

5HT-1 Receptor Agonist

Selective NE RI

Anticholinergic

u opioid-Receptor Agonist, 5HT&NE RI/CNS COX-1&2-Inhibitor

Inhibit protein synthesis

Binds to sterols in fungal cell membrane, changes membrane permeability, allows leakage of intracellular components

Selective Beta-1 blocker/Thiazide combination

Antiepileptic/Antipsychotic

Antibacterial/Sulfonamide

Central presynaptic alpha2-Receptor Antagonist

Nonselective Beta-blocker

H1-Receptor Antagonist/Cough Suppressant

Alpha1-Receptor Blocker

Estrogen/Progestin combination

Reversible AChE Inhibitor

Increases NE metabolism, moderate presynaptic DA agonist, 5HT agonist

Antibacterial/Antiprotozoal

H2-Receptor Antagonist

Increases lipoprotein lipase

Binds to FKBP-12, inhibits calcineurin;blocks T cell activation

Topical antifungal/Adrenocorticoid

Inhibits DNA synthesis through binding to DHFR, inhibiting the formation of reduced folates & thymidylate synthesis

Stabilization of neuronal membranes, modulation of presynaptic transmitter release of excitatory amino acids

Depresses oxygen uptake and carbohydrate

Induces catharsis by strong electrolyte and osmotic effects

Impairs the synthesis of ergosterol

Inhibitor of Acetyl CoA & metabolism of bacterial carbohydrates

Alpha2-Agonist, increases presynaptic inhibition of motor neurons

Progestin hormone

Biguanide antidiabetic/Sulfonylurea

Nonselective B-blocker;reduces aqueous humor formation and increases outflow

Levodopa decarboylation Inhibitor/Precursor of DA

Antiepileptic, Hypnotic

Antineoplastic/Antiestrogen

5-Alpha Reductase Inhibitor and decreasing 5-Alpha-DHT conversion from testosterone

Central action in the spinal cord, inhibiting the flexor & crossed extensor reflexes

Antagonism of NE and DA release from nerve terminals, increases reuptake and inactivation of catecholamines

Antistussive through anesthetizing stretch receptors in the respiratory passages

Selective Beta1-blocker/Diuretic combination

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