G12&13 Flashcards
Dog - Most common oral neoplasms - Most —> Least common
Malignant melanoma
SCC
Fibrosarcoma
Epulides
Feline oral tumours - most common —> Least
SCC
Fibrosarcoma
Melanoma
List clinical signs of an oral NP - 8
Ptyalism Halitosis Inappetence Dysphagia Weight loss Exophthalmos Epistaxis Tooth loss
Oral NP - How is prognosis determined? - 4
Histological type
Location
Size
Stage
What are the 4 subtypes of epulides in canines?
Acanthomatosus - aggressive, invades bone
Fibromatous - Slow growing and firm, maxillary premolar
Ossifying - Slow growing, firm, maxillary premolar
Giant cell - Rare
Canine oral malignant melanoma - Surgical excision
Wide margins
Bone often removed
Canine oral malignant melanoma - Non-resectable, option?
Radiation therapy
Canine oral malignant melanoma - Medical management?
Carboplatin chemo
Immunotherapy?
Vaccines under investigation?
Canine oral malignant melanoma - Prognosis?
Poor
Size and stage determine
Canine oral malignant melanoma - Most common cause of death?
Metastasis
Canine oral SCC - Best option?
Surgical excision
Wide margins
Bone removal often req
Canine oral SCC - If sx not possible?
Radiation therapy
Definitive or palliative
Canine oral SCC - Medical options
Piroicam
Cisplatin and piroxicam - CAUTION, both nephrotic is
Carboplatin = cisplatin alternative
Canine oral SCC - Prognosis?
Good if complete excision
Tonsillar SCC prog poor - high metastatic rate
Canine oral fibrosarcoma - Recommended Tx?
Surgical excision
Wide margins
Often bone removal for local control
Canine oral fibrosarcoma - Incompletely excised tumour Tx?
Definitive radiation therapy
Canine oral fibrosarcoma - Death more commonly due to?
Inadequate local control
Not mets
Canine oral fibrosarcoma - Prog?
Guarded
Canine oral fibrosarcoma - Chemo?
Unknown role
Canine oral epulides - Recommended Tx(s)?
Surgical excision
Often bone removal for local control - esp acanthomatous type
Alternatively, definitive radiotherapy
Canine oral epulides - Prog?
Excellent
Local control = curative
Most —> Least common feline oral tumours - 3
Squamous cell carcinoma
Fibrosarcoma
Malignant melanoma
Feline oral SCC
Invasive?
Prognosis?
Mets?
V locally invasive
Successful Tx difficult
Mets uncommon
Feline oral Fibrosarcoma
Invasive?
Mets?
Locally invasive
Metastatic rate low