G12&13 Flashcards

1
Q

Dog - Most common oral neoplasms - Most —> Least common

A

Malignant melanoma
SCC
Fibrosarcoma
Epulides

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2
Q

Feline oral tumours - most common —> Least

A

SCC
Fibrosarcoma
Melanoma

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3
Q

List clinical signs of an oral NP - 8

A
Ptyalism
Halitosis
Inappetence
Dysphagia
Weight loss
Exophthalmos
Epistaxis
Tooth loss
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4
Q

Oral NP - How is prognosis determined? - 4

A

Histological type
Location
Size
Stage

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5
Q

What are the 4 subtypes of epulides in canines?

A

Acanthomatosus - aggressive, invades bone

Fibromatous - Slow growing and firm, maxillary premolar

Ossifying - Slow growing, firm, maxillary premolar

Giant cell - Rare

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6
Q

Canine oral malignant melanoma - Surgical excision

A

Wide margins

Bone often removed

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7
Q

Canine oral malignant melanoma - Non-resectable, option?

A

Radiation therapy

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8
Q

Canine oral malignant melanoma - Medical management?

A

Carboplatin chemo

Immunotherapy?
Vaccines under investigation?

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9
Q

Canine oral malignant melanoma - Prognosis?

A

Poor

Size and stage determine

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10
Q

Canine oral malignant melanoma - Most common cause of death?

A

Metastasis

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11
Q

Canine oral SCC - Best option?

A

Surgical excision
Wide margins
Bone removal often req

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12
Q

Canine oral SCC - If sx not possible?

A

Radiation therapy

Definitive or palliative

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13
Q

Canine oral SCC - Medical options

A

Piroicam
Cisplatin and piroxicam - CAUTION, both nephrotic is
Carboplatin = cisplatin alternative

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14
Q

Canine oral SCC - Prognosis?

A

Good if complete excision

Tonsillar SCC prog poor - high metastatic rate

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15
Q

Canine oral fibrosarcoma - Recommended Tx?

A

Surgical excision
Wide margins
Often bone removal for local control

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16
Q

Canine oral fibrosarcoma - Incompletely excised tumour Tx?

A

Definitive radiation therapy

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17
Q

Canine oral fibrosarcoma - Death more commonly due to?

A

Inadequate local control

Not mets

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18
Q

Canine oral fibrosarcoma - Prog?

A

Guarded

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19
Q

Canine oral fibrosarcoma - Chemo?

A

Unknown role

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20
Q

Canine oral epulides - Recommended Tx(s)?

A

Surgical excision
Often bone removal for local control - esp acanthomatous type

Alternatively, definitive radiotherapy

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21
Q

Canine oral epulides - Prog?

A

Excellent

Local control = curative

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22
Q

Most —> Least common feline oral tumours - 3

A

Squamous cell carcinoma
Fibrosarcoma
Malignant melanoma

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23
Q

Feline oral SCC

Invasive?
Prognosis?
Mets?

A

V locally invasive
Successful Tx difficult
Mets uncommon

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24
Q

Feline oral Fibrosarcoma

Invasive?
Mets?

A

Locally invasive

Metastatic rate low

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25
Q

Feline oral malignant melanoma - how common?

A

Rare

26
Q

Most common gastric tumour in dog?

A

Adenocarcinoma

27
Q

Most common gastric tumour in cat?

A

Lymphoma

28
Q

Gastric tumour Clin signs?

A

V
Weight loss
Inappetance

29
Q

What type of anaemia is commonly seen with gastric tumours. Why?

A

Microcytic hypochromic

Chronic GI blood loss

30
Q

Gastric tumour Tx?

A

Resection

Difficult

31
Q

5 type of gastric tumour

A
Adenocarcinoma
Lymphoma
Leiomyosarcoma
GI stromal tumour
MCT
32
Q

Most common location of gastric adenocarcinoma?

A

Lesser curvature

33
Q

What paraneoplastic syndrome is associated with gastric leiomyoma/sarcoma?

A

Paraneoplastic hypoglycaemia

34
Q

What is the Tx of choice for canine and feline gastric tumours?

A

Surgical excision

May be difficult due to location and/or stage

35
Q

Gastric adenocarcinoma prog?

A

Benign —> Good

Malignant —> Poor

36
Q

Gastric leiomyoma/leiomyosarcoma prog?

A

Benign —> Good

Malignant —> Guarded to poor

37
Q

Gastrointestinal stromal tumour prog?

A

Guarded to poor

38
Q

Most common intestinal tumour in dog and cat

A

Lymphoma

39
Q

Clin signs of an instestinal/rectal tumour?

A
Weight loss
Inappetance
V
D
Melena and/or Haematochezia
40
Q

3 Most —> Least common canine intestinal tumours

A

Adenocarcinoma
Leiomyoma/Leiomyosarcoma
Gastrointestinal stromal tumour

41
Q

Intestinal adenocarcinoma - most common site in dog?

A

Large intestine

Most common SI location = Jejunum

42
Q

Most common canine intestinal leiomyoma/leiomyosarcoma locations? - 2

A

Jejunum

Caecum

43
Q

Gastrointestinal stromal tumour most common location in canine?

A

LI

44
Q

Most common location of feline intestinal adenocarcinoma?

A

Small intestine

45
Q

Tx for canine and feline intestinal; adenocarcinoma, leiomyoma, leiomyosarcoma, gastrointestinal stromal tumour?

A

Surgical excision
Wide margins
Chemo for systemic disease

46
Q

Primary hepatobiliary tumours more common in?

A

Cats

47
Q

Metastatic hepatobiliary tumours more common in?

A

Dogs

48
Q

Primary hepatobiliary tumours more often malignant in which species?

A

Dog

49
Q

List 4 malignant primary hepatobiliary tumours

A

Hepatocellular carcinoma
Biliary carcinoma
Neuroendocrine tumour
Sarcoma

50
Q

What is the most common primary hepatobilairy tumour in the cat?

A

Biliary cystadenoma

51
Q

What is the most common primary hepatobiliary tumour in the dog?

A

Hepatocellular carcinoma

52
Q

Characteristics of a massive hepatobiliary tumour?

A

Large, solitary mass

Single lobe affected

53
Q

Characteristics of a nodules hepatobiliary tumour?

A

Multifocal

Several lobes affected

54
Q

Characteristics of a diffuse hepatobiliary tumour?

A

All lobes affected

55
Q

Clinical signs of hepatobiliary tumours?

A
Weight loss
Inappetence
V
PUPD
Ascites
If extensive - Icterus, hepatoencephalopathy
56
Q

What paraneoplastic condition is sometimes associated with hepatocellular carcinoma?

A

Hypoglycaemia

57
Q

Most common type of exocrine pancreatic tumour?

A

Adenocarcinoma

58
Q

2 examples of exocrine pancreatic masses

A

Adenomas

Pseudocysts

59
Q

Tx of exocrine pancreatic tumours?

A

Surgical resection

60
Q

Why is surgical resection of an exocrine pancreatic tumour often only palliative?

A

Many animals have mets at time of Dx

61
Q

Exocrine pancreatic tumour - invasiveness and metastatic rate?

A

Locally invasive

Very high metastatic rate