Furosemide

Question 1

What is the brand/trade name for furosemide?

Answer 1

• Lasix

_{Anesthesia Guidebook - Episode 19: Anesthesia Top Drawer Run Down - Part 3
UpToDate - Furosemide: Drug Information}

Question 2

What is the pharmacologic category/class of furosemide?

Answer 2

• Loop diuretic, antihypertensive

_{Anesthesia Guidebook - Episode 19: Anesthesia Top Drawer Run Down - Part 3
UpToDate - Furosemide: Drug Information}

Question 3

What is the mechanism of action of furosemide?

Answer 3

• inhibits the reabsorption of sodium and chloride in the ascending loop of henle → natriuresis

_{Anesthesia Guidebook - Episode 19: Anesthesia Top Drawer Run Down - Part 3
UpToDate - Furosemide: Drug Information}

Question 4

What is the dose and timing of furosemide?

Answer 4

• whatever the surgeon tells you (probs 20-40 mg)
• whenever the surgeon tells you to

_{Anesthesia Guidebook - Episode 19: Anesthesia Top Drawer Run Down - Part 3
UpToDate - Furosemide: Drug Information}

Question 5

What is the onset of action for furosemide?

Answer 5

• ~5 minutes, peak in 30 minutes

_{Anesthesia Guidebook - Episode 19: Anesthesia Top Drawer Run Down - Part 3
UpToDate - Furosemide: Drug Information}

Question 6

What is the duration of action for furosemide?

Answer 6

• ~2 hours

_{Anesthesia Guidebook - Episode 19: Anesthesia Top Drawer Run Down - Part 3
UpToDate - Furosemide: Drug Information}

Question 7

Rapid IV administration of furosemide may cause ___________

Answer 7

• ototoxicity

I heard it’s cuz the subconscious voice screams “I GOTSTA PEE” real loud

_{Anesthesia Guidebook - Episode 19: Anesthesia Top Drawer Run Down - Part 3
UpToDate - Furosemide: Drug Information}