Fungi Flashcards

1
Q

What species causes aspergillosis?

A

Aspergillus fumigatus or flavus

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2
Q

What are the clinical forms of aspergillus infection?

A

Allergic bronchopulmonary aspergillosis
Aspergilloma
Invasive aspergillosis

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3
Q

What are the features of allergic bronchopulmonary aspergillosis and how do you manage it?

A

Severe asthma
Chronic cough
Eosinophilia

Steroids and itraconazole

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4
Q

What are the features of aspergilloma and how do you manage it?

A

Fungal ball develops in prexisting cavity
Haemoptysis

Surgery and itraconazole

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5
Q

What are the features of invasive aspergillosis and how do you treat it?

A

Occurs in brain, kidney, liver and skin

Amphotericin B

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6
Q

What are the forms of histoplasmosis and what causes them?

A

Small form - histoplasma capsulatum var capsulatum

Large form- histoplasma capsulatum var duboisii

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7
Q

What are the features of small form histoplasmosis and where is it found?

A

Americas, Asia and E Africa

Acute of chronic pulmonary infections
Pericarditis
Disseminated affecting BM, spleen, liver, LNs
Oral ulceration

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8
Q

What are the features of large form histoplasmosis and where is it found?

A

Central and west Africa

Focal of bone, skin, LNs
Disseminated affecting mucosal surfaces

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9
Q

What causes blastomycosis and where is it found?

A

Blastomyces dermatitidis

N America, Africa, India, Middle East

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10
Q

What are the features of blastomycosis?

A

Chronic pulmonary or disseminated disease(skin and lung)
Upper lobes
Can get lytic bone lesions
Rash: verrucous lesions with irregular borders, impetigo like

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11
Q

What causes coccidiomycosis and where is it found?

A

Coccidioides immitis

Americas

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12
Q

What are the features of coccidioidomycosis?

A

Dissemination with advanced HIV

Meninges, joints, skin

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13
Q

What causes paracoccidioidomycoses and where is it found?

A

Paracoccidioides braziliensis

South and Central America

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14
Q

What are the features of paracoccidioidomycoses?

A
Hepatosplenomegaly 
Fever and weight loss
Lytic bone lesions
Lung disease only when chronic- Apices spared
Painful lesions in mouth
Ulcerative/crusty lesions
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15
Q

What causes penicilliosis and where is it found?

A

Talaromyces marneffei

SE Asia

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16
Q

What are he features of penicilliosis?

A

Hepatosplenomegaly
Skin lesions like molluscum
LNs
Anaemia

17
Q

What does sporothrix schenkii cause and where is it found?

A

Serpiginous ulcerated lesions up lymphatic tract
Disseminated disease in PLHIV

Worldwide- most common in S America