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Infections > Fungal Infections > Flashcards

Fungal Infections Flashcards

1
Q

What is Aspergillosis and how to treat it

A

Mould infection usually affecting breathing/lungs

Treatment: Voriconazole

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2
Q

What is Cryptococcosis and how to treat it

A

Lung or brain infection usually in immunocompromised

Treatment: Amphotericin B

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3
Q

How to treat Vaginal thrush

A

1st Line:
Clotrimazole / Fluconazole

2nd Line:
Itraconazole

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4
Q

How treat oral thrush

A

1st Line:
Nystatin / Miconazole / Fluconazole

2nd Line:
Itraconazole

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5
Q

How to treat Skin / Nail infections

A

1st Line:
Topical therapy

2nd Line:
Systemic (Itraconazole / terbinafine)

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6
Q

How to treat Ringworm (Tinea): All body parts apart from Nails

A

1st Line:
Topical Anti-fungal

2nd Line:
Terbinafine

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7
Q

How to treat Ringworm (Tinea): Nails

A

Amorolfine Nail Laqure

Once weekly (for up to 1 year)

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8
Q

When should you refer Ringworm (NAIL)

A
  • under 18
  • more than 2 nails infected
  • diabetic
  • Pregnant / breasfeeding
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9
Q

Which Anti-fungal Medication causes Hepatotoxicity

A
  • Fluconazole
  • Itraconazole
  • Ketoconazole
  • Voriconazole
  • Terbinafine
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10
Q

Which Anti-fungal Medication that causes Hepatotoxicity is the most potent

A

Ketoconazole

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11
Q

Which Anti-fungal Medication causes QT prolongation

A
  • Fluconazole
  • Itraconazole
  • Ketoconazole
  • Voriconazole
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12
Q

Which of the Anti-fungal Medication that cause QT prolongation is the least potent

A

Fluconazole

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13
Q

Which Anti-fungal Medication has an increased bioavailability with carbonated drinks

A

Itraconazole

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13
Q

Which Anti-fungal Medication would you need to be careful in sunlight

A

Voriconazole

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14
Q

Which Anti-fungal Medication would you may need to be careful in sunlight

A

Voriconazole

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15
Q

Which Anti-fungal Medication would you need to have caution in renal failure

A

Amphotericin B

16
Q

What does IV Amphotericin B have a risk of and what should you do when administering

A

Hypersensitivity reaction

(30 minute observation after giving 1 dose)

17
Q

How to treat and prevent IV Amphotericin B Hypersensitivity reaction

A

Treat with…
Corticosteroids

Maintain same formulation to help prevent

Infections (16 decks)

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