Fungal Derm Flashcards
Candidiasis
- candida albicans most common
- infects skin and mucus membranes
- reproduce via budding
- failure of body to control growth
- likes to grow in warm, dark, moist areas eg groin, axilla
CANDIDA BALANITIS
- Definition
- Etiology
- infection and inflammation of glans penis
2. Candida albicans
CANDIDA BALANITIS
- Predisposing conditions
- Clinical features
- uncircumcised males, DM, immunosuppression, antibiotic use; may or may not be associated w/ intercourse w/ infected partner
- tenderness, edema, erythematous papules/pustules/erosions, exudate, satellite lesions, inability to retract foreskin
CANDIDA BALANITIS
- Diagnosis
- Differential diagnosis
- clinical presentation, location, KOH, cultures
2. molluscum contagiosum, warts, psoriasis, eczema, herpes, squamous cell carcinoma, scabies
CANDIDA BALANITIS
- Treatment
- Prevention
- topical antifungal, look for cause (eg uncontrolled DM), gentle retraction of foreskin and soak in warm water; avoid steroids! (can get rebound)
- keep skin dry, hygiene, powders, yogurt, probiotics
CANDIDA INTERTRIGO
- Definition
- Etiology
- superficial infection of intertriginous areas
2. candida albicans
CANDIDA INTERTRIGO
- Predisposing conditions
- Clinical features
- obesity, pendulous breasts, DM, poor hygiene, tight clothing, hot/humid weather
- erythematous macerated (super wrinkly like under a band aid) skin, glistening, bilateral, satellite lesions, pruritus; common sites - groin, gluteal folds, under breast or panna, axilla
CANDIDA INTERTRIGO
- Diagnosis
- Differential diagnosis
- clinical presentation, location, KOH/culture
2. staph/strep, psoriasis, seborrhea, atopic, erythrasma
CANDIDA INTERTRIGO
- Treatment
- Prevention
- topical antifungal, vinegar wet dressings, burrows solution, air, proper hygiene
- powders, ointments, weight loss, zinc oxide ointment (Desitin)
ORAL CANDIDIASIS (THRUSH)
- Definition
- Etiology
- mucous membrane infection (of the mouth, palate, esophagus, pharynx)
- candida albicans
ORAL CANDIDIASIS (THRUSH)
- Predisposing conditions
- Clinical features
- neonate, DM, antibiotic use, HIV, immunosuppression, steroid therapy (if you see this in adult, be suspicious of DM or HIV)
- burning, diminished taste; stuck-on creamy exudates/plaques with underlying erythema; can be asymptomatic
ORAL CANDIDIASIS (THRUSH)
- Diagnosis
- Differential Diagnosis
- Treatment
- appearance, KOH
- lichen planus, geographic tongue, oral hairy leukoplakia, condyloma acuminatum
- topical antifungals
ANGULAR CHEILITIS (Perleche)
- Definition
- Etiology
- inflammation, superficial infection at angles of mouth, secondary to saliva maceration
- candida, chronic irritation
ANGULAR CHEILITIS (Perleche)
- Predisposing conditions
- Clinical features
- lip licking, elderly, dentures, mouth breathing, Accutane use
- macerated angles of mouth, erythema, fissures
ANGULAR CHEILITIS (Perleche)
- Diagnosis
- Differential diagnosis
- Treatment
- clinical presentation, location, cultures
- candida, staph infection, B12 deficiency, lichen planus, contact dermatitis, impetigo, intertrigo
- topical antifungal, barriers, address underlying cause, aquaphor (vaseline-type barrier)
PITYRIASIS (TINEA) VERSICOLOR
- Definition
- Etiology
- superficial fungal infection; chronic, asymptomatic dermatosis of the torso
- Malassezia furfur, M globosa
PITYRIASIS (TINEA) VERSICOLOR
- Predisposing conditions
- Clinical features
- oily skin, heat, moisture, sweating, pregnancy, steroid use, poor nutrition, immunodeficient
- macule with fine scale, patches, vitiligo appearance (pale/white patches due to melanocyte malfunction), insidious (slow/subtle) onset
PITYRIASIS (TINEA) VERSICOLOR
- Diagnosis
- Differential diagnosis
- appearance, KOH, Wood’s lamp (pale yellow, white, or green)
- vitiligo, seborrheic dermatitis, syphilis, psoriasis, eczema, tinea corporis
PITYRIASIS (TINEA) VERSICOLOR
- Treatment
- Complications
- topical antifungal (selsun blue shampoo), selenium sulfide, oral?, wash clothing, sunlight may accelerate re-pigmentation
- pigment changes, recurrence
Tinea
- dermatophyte
- group of fungi capable of infecting skin, hair, nails
- most common of all mucocutaneous infections
- predisposing: wrestlers, pets, etc
TINEA CAPITIS
- Definition
- Etiology
- scalp infection; most common dermatophytosis in kids; invasion of stratum corneum and hair shaft with fungal hyphae
- Tricophyton (90%)»_space; Microsporum
TINEA CAPITIS
- Predisposing conditions
- Clinical features
- pets/cats, close contact, malnutrition, kids, rural (soil), debilitation/limited mobility
- seborrheic vs. noninflammatory vs pustular; lymphadenopathy (occipital), inflammatory (kerion)
TINEA CAPITIS
- Diagnosis
- Differential diagnosis
- Treatment
- clinical presentation, KOH, Wood’s lamp for microsporum (bright green), cultures
- seborrhea (cradle cap), psoriasis, eczema, alopecia, lichen simplex, scabies
- oral and topical antifungal, clean contaminated objects, treat family if needed
KERION
- Definition
- Etiology
- inflammatory (sterile?) scalp infection
2. Tricophyton, Microsporum
KERION
- Predisposing conditions
- Clinical features
- chronic carrier state, DM, children, friction, ingrown hairs, malnutrition, EtOH, hyperhidrosis, obesity, athletes
- tender, boggy area; fever; alopecia; lymphadenopathy
KERION
- Diagnosis
- Differential diagnosis
- Treatment
- appearance, KOH, Wood’s lamp for Microsporum
- hidradenitis suppurativa, herpes simplex, ruptured cyst, furuncle/carbuncle
- refer to specialist; likely to scar; very difficult to treat
TINEA CORPORIS
- Definition
- Etiology
- trunk/body infection, “ring worm”
2. Tricophyton rubrum, Microsporum canis or tonsurans
TINEA CORPORIS
- Predisposing conditions
- Clinical features
- warm climates, contact, other tinea infections, contaminated soil
- scaly papules/macules, raised sharply marginated border, itch, chronic, borders extend and leave central clearing or brownish color
TINEA CORPORIS
- Diagnosis
- Differential diagnosis
- Treatment
- clinical presentation, location, cultures, KOH, Wood’s lamp
- eczema, psoriasis, dermatitis, tinea/pityriasis versicolor
- NO STEROIDS; topical antifungal or oral
TINEA CRURIS
- Definition
- Etiology
- tinea of the groin, “jock itch”
2. T. rubrum or T. mentagrophytes
TINEA CRURIS
- Predisposing conditions
- Clinical features
- location, swimming, sweating, obesity, steroids, males, tinea pedis
- itching increases as moisture increases, bilateral plaques with scale, erythema or brown, spares the penis/scrotum but migrates to butt
TINEA CRURIS
- Diagnosis
- Differential diagnosis
- Treatment
- appearance, KOH, culture, Wood’s lamp
- intertrigo, psoriasis
- drying well, hygiene, topical antifungals, powders; treat pedis/manus; avoid restrictive clothing
TINEA MANUS
- Definition
- Etiology
- fungal hand infection
2. T. rubrum
TINEA MANUS
- Predisposing conditions
- Clinical features
- tinea pedis/cruris
2. scaling, itch, papules, bullae (look different on dorsal vs. volar surface)
TINEA MANUS
- Diagnosis
- Differential diagnosis
- Treatment
- appearance, KOH
- eczema, dermatitis, psoriasis, SCC, lichen simplex
- treat other regions; topical/oral antifungals (topicals often fail), hygiene, can recur if nails not clear
TINEA PEDIS
- Definition
- Etiology
- fungal infection, athlete’s foot
2. T. rubrum, T. mentagrophytes, E. floccusum
TINEA PEDIS
- Predisposing conditions
- Clinical features
- gym use, sweating, atopic
- many variations; scaling, macerated, erythema, bulla formation, moccasin distribution, between digits, dorsal foot, toenails
TINEA PEDIS
- Diagnosis
- Differential diagnosis
- clinical presentation/location, cultures, KOH, negative Wood’s lamp
- psoriasis, staph, contact dermatitis, impetigo, eczema
TINEA PEDIS
- Treatment
- Prevention
- change socks, air, hygiene (shower shoes, dry well), antifungals
- aquasocks