fundamentals quiz 2 Flashcards

1
Q

Types of Hypersensitive reactions

A
Type 1: Rapid hypersensitivity reactions
Type 2: Cytotoxic reactions 
Type 3: Immune complex reactions 
Type 4: Delayed hypersensitivity reactions
Type 5: Stimulation Reaction
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2
Q

Rapid hypersensitivity reactions

A
  • Happens right away
  • Also called atopic allergy, the most common type of hypersensitivity
  • Reaction of IgE antibody on mast cells with antigen
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3
Q

Cytotoxic reactions

A
  • Blood transfusion reaction
  • The body makes special autoantibodies directed against self cells that have some form of foreign protein attached to them.
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4
Q

Immune complex reactions

A

Excess antigens cause immune complexes to form in the blood. These circulating complexes usually lodge in small blood vessels.

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5
Q

Delayed hypersensitivity reactions

A
  • The reactive cell is the T-cell.
  • Hours to days after exposure.
  • Ex. TB test
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6
Q

Stimulatory reaction

A

Excess stimulation of a normal cell surface receptor by an autoantibody, resulting in continuous “turned-on” state for the cell.

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7
Q

Osteoarthritis

A
  • autoimmune disease
  • Most common type of arthritis
  • Joint pain and loss of function characterized by progressive deterioration and loss of cartilage in the joints.
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8
Q

Rheumatoid arthritis

A
  • Autoimmune disease
  • one of the most common connective tissue diseases and the most destructive to the joints.
  • Chronic, progressive, systemic inflammatory disease affecting primarily the synovial joints.
  • Autoantibodies formed that attack healthy tissue, causing inflammation.
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9
Q

Passive Immunity

A

Short duration, either naturally by placental transfer or artificially by injection of antibodies.

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10
Q

Active Immunity

A

Lasts for years and occurs naturally by infection or artificially by stimulation (vaccine) of immune defenses.

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11
Q

Pathogen

A

Any microorganism capable of producing disease.

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12
Q

Basophils

A

Release histamine and heparin in areas of tissue damage.

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13
Q

Eosinophil

A

Weak phagocytic action; releases vasoactive amines during allergic reactions.

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14
Q

Natural active immunity

A

when an antigen enters the body without human assistance and the body actively responds making antibodies. The human will not become infectious a second time. ex. chicken pox

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15
Q

Artificial active immunity

A

Protection by vaccination or immunization. Antigens are placed into the human and the person actively produces antibodies against the antigen.

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16
Q

Natural passive immunity

A

Occurs when antibodies are passed from mother to the fetus via placenta or breast milk.

17
Q

Artificial passive immunity

A

Injecting a person with antibodies that were produced in another person or animal. ex. poisonous snake bites

18
Q

Suppressor T-cells

A

Prevent hypersensitivity (immune overreactions) on exposure to non-self cells. Prevents formation of antibodies against normal, healthy self cells.

19
Q

Natural killer cells

A

Have a direct cytotoxic effect on some non-self cells. They conduct “seek and destroy” missions in the body to eliminate non-self cells.

20
Q

Inflammation “Natural Immunity”

A

Provides immediate protection against the effects of tissue injury and foreign proteins. The ability for an inflammatory response is critical to health and well-being.

21
Q

B-lymphocyte

A

Becomes sensitized to foreign cells and proteins. A type of white blood cell that circulates in the blood and lymph and produces antibody.

22
Q

Platelets

A

Help the blood clot. Smaller than red or white blood cells.

23
Q

Erythrocyte (red blood cell)

A

A blood cell of vertebrates that transports oxygen and carbon dioxide

24
Q

Plasma cell

A

A type of immune cell (white blood cell) that makes large amounts of a specific antibody.

25
Q

Lymphocytes

A

A type of immune cell that is mad in the bone marrow and id found in the blood and lymph tissue.

26
Q

Carcinogenesis

A

The creation of cancer

27
Q

Metastasis

A

Movement or spreading of cancer cells from one organ or tissue to another.

28
Q

Cancer cells usually spread through the blood or the lymph system

A

!

29
Q

Papule

A

A solid, raised spot on the skin that is up to 0.5 cm wide. It is a type of skin lesion.

30
Q

Macule

A

A flat, distinct area of skin that is usually less than 1 cm wide. It usually does not include a change in skin texture or thickness.

31
Q

Vesicle

A

A small sac or cyst containing fluid or gas.

32
Q

Pustules

A

Small, inflamed, pus-filled, blister-like lesions on the skin surface.

33
Q

Petechia

A

pinpoint, round spots that appear on the skin as a result of bleeding under the skin.

34
Q

Eschar tissue

A

A dry scab or slough formed on the skin as a result of a burn or by the action of a corrosive or caustic substance.

35
Q

Granulation tissue

A

A mass of new connective tissue and capillaries formed on the surface of a healing ulcer or wound.

36
Q

Virulence

A

Extremely infectious, malignant, or poisonous. Used of a disease or toxin.

37
Q

Antibody

A

A protein produced by the body’s immune system when it detects harmful substances called antigens.