Fundamentals of pharmacology Flashcards

1
Q

The science deals with studying the biochemical and physiological aspects of drug effects, including absorption, distribution, metabolism, excretion, toxicity, and specific mechanism of drug action

A

PHARMACOLOGY

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2
Q

Study of substances that interact w/ living systems through chemical processes, especially by binding to regulatory molecules & activating or inhibiting normal
processes

A

PHARMACOLOGY

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3
Q

Study of selective biologic activity of drugs

A

PHARMACOLOGY

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4
Q
  • the study of the action of drugs on living tissue, the study of the biochemical and physiological effects of drugs and their mechanism of action.
A

PHARMACODYNAMICS

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5
Q

a study of the processes of drug absorption, distribution, metabolism, and excretion

A

PHARMACOKINETICS

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6
Q

study of the use of drugs in treating diseases

A

PHARMACOTHERAPEUTICS

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7
Q

a study of the amount of drugs that are required to produce a therapeutic effect

A

POSOLOGY

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8
Q

the science of identification, selection, preservation, standardization, compounding, and dispensing of medicinal substances

A

PHARMACY

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9
Q

study of the harmful effects of drugs on living tissue, including the diagnosis and treatment thereof

A

TOXICOLOGY

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10
Q

a study of drugs’ physical and chemical properties together with a description of their identification and sources.

A

PHARMACOGNOSY

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11
Q

Substances that act on biologic systems at the chemical (molecular) level and alter
their functions

A

DRUGS

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12
Q

❑ Any substance or product that is used or intended to be used to modify physiological
systems or pathological states for the recipient’s benefit.
❑ Articles for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in man or other animals
❑ Articles other than food intended to affect the structure or any function of the body of man or other animals

A

DRUGS

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13
Q

The molecular components of the body with which drugs

interact to bring about their effects

A

Drug receptors

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14
Q

Drugs are chemicals that modify body functions.

They may be __

A

Nature of drugs

ions, carbohydrates, lipids, or proteins

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15
Q

THE NATURE AND SOURCES OF DRUGS

A

MAPSMD

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16
Q

Mineral

A

Liquid Paraffin, Magnesium Sulfate, Fe, etc.

17
Q

Animal

A

Insulin, Thyroid, Epinephrine

18
Q

Plant

A

Morphine, Quinine, Alkaloids

19
Q

Microorganism

A

Penicillin & other antibiotics

20
Q

Drugs produced by genetic engineering

A

Human Insulin, human growth hormones

21
Q

Naming of drugs (4)

A

CHEMICAL NAME
GENERIC NAME
OFFICIAL NAME
BRAND NAME

22
Q

Alters certain physiologic functions & activities of body cells

A

FUNCTIONAL MODIFIERS

23
Q

Functional modifiers

 The sensation of pain
 Tachycardia
 Morphine→
 Bevacizumab →

A
  1. (analgesics, anesthetics)
  2. (beta-blockers)
  3. narcotic analgesic; pain perception
  4. for cancer; inhibit VRGF (vascular endothelial
    growth factor) → vascularization
24
Q

Replaces/ replenish endogenous substance that are lacking/ deficient/ absent

A

REPLENISHERS

25
Q

an autoimmune disease when the immune system produces
antibodies that target the parietal cells of the stomach that leads to inhibiting/decreasing HCL & Intrinsic Factor (which are
important in VitB12 absorption

A

Pernicious Anemia (Vit B12)

26
Q

having pernicious anemia can lead to __

A

Megaloblastic Anemia

27
Q

Causes of VitB12 deficiency

A

a. Chronic use of Proton pump Inhibitor
b. H2 Blockers
c. Diphylobotrium latum (fish tapeworm)

28
Q

Diagnosis or confirmation of a diagnosis of certain diseases

A

DIAGNOSTIC AGENTS

29
Q

Myasthenia gravis

A

Edrophonium (Tensilon®)

30
Q

diagnosis of bronchial asthma (Histamine)

A

Pulmonary challenge test

31
Q

to visualize the outline of the GIT (Barium sulfate)

A

Radiopaque

32
Q

Schemia

A

Dobutamine

33
Q

used in pharmacologic stress testing

A

Dobutamine/ Dipyridamole

34
Q

Agents used to kill/ inhibit the growth of cells considered as foreign to the
bodyv

A

CHEMOTHERAPEUTICS AGENTS

35
Q

CHEMOTHERAPEUTICS AGENTS

A

 Anti-infectives
 Anti-microbials
 Anti-neoplastic
 Anti-cancer

36
Q

Explains how a drug produces its effects

A

MECHANISM OF ACTION

37
Q

NON TARGET PROTEIN-MEDIATED

A

a. DIRECT CHEMICAL INTERACTION

b. COLLIGATIVE MECHANISM/MASS EFFECT