Fundamentals of Parasitology Flashcards

1
Q
The definitive diagnosis of parasitic infections is frequently made by the examination of stool samples for 'ova and parasites'. Which parasite may produce ova that are however not found in stool but may be present elsewhere?
Trichinella spiralis
Entamoeba histolytica
Trichomonas hominis
Necator americanus
Enterobius vermicularis
A

Enterobius vermicularis

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2
Q

Which of the following statements is NOT characteristic of infections by Wuchereria bancrofti?
A. The immune response contributes to both control of the infection and pathology associated with the disease

They are transmitted by several genera of mosquitoes

The organism is an important cause of blindness in endemic areas

Infections may be treated with diethycarbamazine

Microfilariae may be found in the blood stream

A

Tissue nematodes Filaria
Mosquitoes
Wuchereria bancrofti
Brugia malayi/timori

Black fly: onchocerca volvulus

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3
Q
A school teacher was posted to a rural school where the classroom windows were not screened. As a result, she got bitten by tse tse flies. What organism was she most probably exposed to as a result of the bites?
Trypanosoma cruzi
Leishmania donovani
Wuchereria bancrofti
Necator americanus
Trypanosoma gambiense
A

Trypanosoma gambiense: african sleeping sickness-parasites in CNS; also t ehodesience

Trypanosoma cruzi: CHAGAS Disease
Leishmania donovani
Wuchereria bancrofti: mosquito
Necator americanus

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4
Q
A protozoan with characteristic jerky motility is most commonly observed in of the following?
Vaginal secretions
Duodenal contents
Blood
Biopsied muscle
Sputum
A

Vaginal secretions

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5
Q
A helminth that is naturally transmitted by ingestion of pork, bear, or walrus meat could be detected in in which of the following?
Vaginal secretions
Duodenal contents
Blood
Biopsied muscle
Sputum
A

Biopsied muscle

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6
Q
A parasite that is acquired from the ingestion of crab or crayfish may produce eggs that may be found in which of the following?
Vaginal secretions
Duodenal contents
Blood
Biopsied muscle
Sputum
A

Sputum

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7
Q
Persons who live in a rural area often complain about getting bitten by sand flies while dining in the open air. What potentially pathogenic organism may be transmitted by the sand flies?
Wuchereria bancrofti
Loa loa
Trypanosoma cruzi
Balantidum coli
Leishmania major
A

Leishmania major: vector SAND FLY- CHAGAS DISEASE: enlarged heart and intestine!

Wuchereria bancrofti: mosquito
Loa loa- deer fly
Trypanosoma cruzi
Balantidum coli- ingestion on cysts, intestine-cysts in feces

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8
Q

Which of the following is LEAST LIKELY to be the cause of gastrointestinal or liver problems following the ingestion of seafood?

Diphylobothrium latum
Clonorchis sinensis
Heterophyes heterophyes
Fasciola hepatica
Opisthorchis felineus
A

Fasciola hepatica: liver fluke - plant/vegetable

Diphylobothrium latum: raw fish tapeworm - intestinal disease - megalobastic anemia

Clonorchis sinensis: liver fluke - p westermanii - crab

Heterophyes heterophyes: intestinal fluke - fish

Opisthorchis felineus

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9
Q
Many students presented to the health clinic with fever and body ache following a weekend hiking trip in Connecticut. They reported being repeatedly bitten by ticks that were abundant in the woods. What organism do the ticks most likely transmit?
Entamoeba coli
Babesia microti
Clonorchis sinensis
Dientamoeba fragilis
Enterobius vermicularis
A

Babesia microti: tick vector for Lyme disease

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10
Q
A 5-year-old boy had reportedly been well until about three weeks before he was taken to a clinic. He was small for his age and he complained about vague abdominal pain with nausea. He was anorexic and had constipation for a few days.  An examination of feces revealed the presence of ova with a thick shell. Which of the following was the most probable diagnosis?
Amoebiasis
Ascariasis
Guineaworm
Cysticercosis
Trichuriasis
A

Ascariasis

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11
Q
A Peace Corps volunteer has just returned from India. While he was in Calcutta, he developed a fever with headache and muscle ache. He received analgesics, which reduced his fever, but the fever returned and was accompanied by intense shaking chills, sweating and exhaustion. A blood smear was examined and this revealed the presence of intraerythrocytic organisms with a ‘signet ring’ shape. What is the most probable diagnosis?
Leishmaniasis
Trypanosomiasis
Trichinosis
Malaria
Shigellosis
A

Malaria

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12
Q
Which of the following organisms is a frequent cause of infection found at day-care centers in the United States?
Taenia saginata
Ascaris lumbricoides
Strongyloides stercoralis
Giardia lamblia
Enterobius vermicularis
A

Enterobius vermicularis: very common in USA - pinworm

Taenia saginata: beef tapewrok - ontestinal disease
t. solium: pork tapework - intestine n tissue disease
Giardia lamblia: explosive diarrhea; smelly, fat stool

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13
Q
The lesions caused by Schistosoma japonicum are most usually found within which of the following tissues?
Renal tubules
Intestinal venules
Lung parenchyma
Nasal sinuses
Ocular conjunctiva
A

s. japonicum and masoni: Intestinal venules

s. haematobium: bladder

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14
Q
Which is the form of the malaria parasite that may be transmitted from person to person?
Sporozoite
Gametocyte
Merozoite
Hypnozoite
Tachyzoite
A

Merozoite

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15
Q
Which of the following organisms is most usually found in macrophages?
Plasmodium vivax
Ascaris lumbricoides
Leishmania tropica
Trypanosoma rhodesiense
Trichinella spiralis
A

Leishmania tropica
sandfly
L. donovanii - visceral…most severe

amasyogotes: found in M1 in all forms of disease

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16
Q

A 23-year-old student who occasionally enjoyed a game of beach volleyball presents at the Health Center with a curious skin problem. He had multiple reddish purple pruritic lesions on the soles of both feet. A few hours later, it became painful for him to stand. Serpiginous lines had spread over the dorsum of the feet. What is the most probable diagnosis?

Ground itch due to human hookworm larvae

Swimmer’s itch due to schistosome larvae

Cutaneous larva migrans due to dog hookworm larvae

Madura foot due to Pseudoallescheria boydii

Creeping eruption due to Bartellona hermsii

A

Cutaneous larva migrans due to dog hookworm larvae

17
Q
A middle-aged man was under treatment with corticosteroids for asthmatic bronchitis when he developed unexplained recurrent gram-negative sepsis. He also had a cough with abdominal pain and diarrhea. A CT scan and biopsy of his abdomen revealed the presence of numerous larvae attached to the mucosa. There was also a thickening of the intestinal wall. Which of the following organisms was the most probable cause of the symptoms?
Ascaris lumbricoides
Strongyloides stercoralis
Wuchereria bancrofti
Dracunculus medinensis
Enterobius vermicularis
A

Strongyloides stercoralis - threadworm - infective larvae penetrate skin (ground itch)

Ascaris lumbricoides: most common-ingestion of eggs - adult in the intestine - thick walled eggs in feces

18
Q
A 28-year-old woman, known to be positive for HIV-1, presented with diarrhea of nearly two months duration. The diarrhea was watery and non-bloody and was most severe after meals. A 20-pound weight loss was noted over this period.  Stool culture was negative for enteric bacteria. White blood cells were absent but acid-fast oocysts were found. Which of the following organisms was most probably responsible for the diarrhea?
Entamoeba histolytica
Giardia lamblia
Cryptosporidium parvum
Trichomonas hominis
Enteromonas intestinalis
A

Cryptosporidium parvum

19
Q
Which of the following stages of the malaria parasite may be responsible for relapses months or years after parasite clearance from the circulation?
Schizont
Merozoite
Tachyzoite
Hypnozoite
Bradyzoite
A

Hypnozoite

20
Q
A patient presents with a pruritic erythematous rash, epigastric pain, microcytic hypochromic anemia and hypoalbuminemia. Which of the following diseases would you suspect?
Ascariasis
Trichuriasis
Hookworm
Trichinosis
Malaria
A

Hookworm