Fundamentals (Final Exam)

Question 1

what type of enzyme activity does CYP2C9*1 have

Answer 1

normal

Question 2

what type of enzyme activity does CYP2C9* 2 and *3 have

Answer 2

decreased (50%) and decreased (80&) respectively

Question 3

what metabolizer status would someone with CYP2C91/1 have

Answer 3

extensive metabolizer (EM)

Question 4

what metabolizer status would someone with CYP2C91/2 have

Answer 4

high Intermediate metabolizer (IM)

Question 5

what metabolizer status would someone with CYP2C91/3 have

Answer 5

intermediate metabolizer (IM)

Question 6

what metabolizer status would someone with CYP2C92/3 have

Answer 6

poor metabolizer (PM)

Question 7

what metabolizer status would someone with CYP2C93/3 have

Answer 7

poor metabolizer (PM)

Question 8

what enzyme activity would CYP2C19*1 have

Answer 8

normal

Question 9

what enzyme activity would CYP2C19*2 and *3 have

Answer 9

none

Question 10

what enzyme activity would CYP2C19*9 have

Answer 10

decreased

Question 11

what enzyme activity would CYP2C19*17 have

Answer 11

increased

Question 12

what metabolizer status would someone with CYP2C191/1 have

Answer 12

extensive metabolizer (EM)

Question 13

what metabolizer status would someone with CYP2C191/2 or 3 have

Answer 13

high intermediate metabolizer (IM)

Question 14

what metabolizer status would someone with CYP2C192/9 have

Answer 14

intermediate metabolizer (IM)

Question 15

what metabolizer status would someone with CYP2C192/3 have

Answer 15

poor metabolizer (PM)

Question 16

what metabolizer status would someone with CYP2C1917/17 have

Answer 16

ultra metabolizer (UM)

Question 17

what enzyme activity would CYP2D6*1 have

Answer 17

normal

Question 18

what enzyme activity would CYP2D6*3, *4, *5, *6 have

Answer 18

none

Question 19

what enzyme activity would CYP2D6*9, *10, *17 have

Answer 19

decreased

Question 20

what enzyme activity would CYP2D6*1XN have

Answer 20

increased

Question 21

what metabolizer status would someone with CYP2D61/1 have

Answer 21

extensive metabolizer (EM)

Question 22

what metabolizer status would someone with CYP2D61/3/4/5/6 have

Answer 22

high intermediate metabolizer (IM)

Question 23

what metabolizer status would someone with CYP2D63/9/10/17 have

Answer 23

intermediate metabolizer (IM)

Question 24

what metabolizer status would someone with CYP2D63/3/4/5/6 have

Answer 24

poor metabolizer (PM)

Question 25

what metabolizer status would someone with CYP2D61/1XN have

Answer 25

ultra metabolizer (UM)