Fund. Success Ch. 31 Flashcards
Federal government
Protects the health of the people by ensuring that medications are safe and effective. Currently, the Food and Drug Administration ensures that all medications undergo vigorous testing before they are sold.
State government
Conform to federal legislation but also have additional controls such as alcohol and tobacco.
Health care institutions
Have individual policies to meet federal and state regulations.
Nurse Practice Act
Defines the scope of a nurse’s professional functions and responsibilities.
Define chemical name.
Provides an exact description of the medication’s composition and molecular structure.
Define generic name.
Is created by the manufacturer who first develops the medication; this becomes the official name.
Define trade name.
Is one that the manufacturer has trademarked to identify the particular version they manufacture.
A medication classification indicates:
the effect of the medication on a body system, the symptoms the medication relieves, or the medication’s desired effect.
The form of the medication determines its:
Route.
Pharmacokinetics is:
The study of how medications enter the body, reach their site of action, metabolize, and exit the body.
Absorption is:
Refers to the passage of medication molecules into the blood from the site of administration.
Identify factors that influence drug absorption.
Route of administration, ability of the medication to dissolve, blood flow to the site of administration, body surface area, lipid solubility.
Identify the factors that affect the rate and extent of medication distribution.
Circulation, membrane permeability, protein binding, metabolism, excretion.
Explain the role of metabolism.
After a medication reaches its site of action, it becomes metabolized into a less active or inactive form that is easier to excrete.
Identify the primary organ for drug excretion, and explain what happens if this organ’s function declines.
The kidneys are the primary organ for drug excretion. When renal function declines, a patient is at risk for medication toxicity.
Define therapeutic effects.
Are the expected or predictable physiological response to a medication.
Define side effects.
Are predictable and often unavoidable secondary effects a medication predictably will cause.
Define adverse effects.
Are unintended, undesirable, and often unpredictable severe responses to a medication.
Define toxic effects.
Develops after prolonged intake of a medication or when a medication accumulates in the blood because of impaired metabolism or excretion.
Define idiosyncratic reactions.
Are unpredictable effects in which a patient overreacts or underreacts to a medication or has a reaction that is different from normal.
Define allergic reactions.
Are unpredictable responses to a medication.
Define anaphylactic reactions.
Are allergic reactions that are life threatening and characterized by sudden constriction of bronchiolar muscles, edema of the pharynx and larynx, and severe wheezing and shortness of breath.
Define medication interaction.
Occurs when one medication modifies the action of another medication; it may alter the way another medication is absorbed, metabolized, or eliminated from the body.
Define synergistic effect.
Is when the combined effect of the two medications is greater than the effect of the medications when given separately.
Define effective concentration (MEC).
Is the plasma level of a medication below when the medication’s effect will not occur.
Define peak concentration.
Is the highest serum level concentration.
Define trough concentration.
Is the lowest serum level concentration.
Define biological half life.
Is the time it takes for excretion processes to lower the serum medication concentration by half.
Identify the three types of oral routes.
Oral, buccal, sublingual.
List the four major sites for parenteral injections.
Intradermal, subcutaneous, intramuscular, intravenous.
Define epidural.
Are administered in the epidural space via a catheter, usually used for post operative analgesia.
Define intrathecal.
Is via a catheter that is in the subarachnoid space or one of the ventricles of the brain.
Define intraosseous.
Is administered directly into the bone marrow, it is commonly used in infants and toddlers.
Define intraperitoneal.
Such as chemotherapeutics, are administered directly into the peritoneal cavity.
Define intrapleural.
Commonly chemotherapeutics, are administered directly into the pleural space.
Define intraarterial.
Administered into the arteries.
Define intracardiac.
Directly into cardiac tissue.