Functions Flashcards
What are the main functions of the liver?
Regulate blood glucose
Store vitimans and glycogen
Remove hormones and old RBCs
Detoxify alcohol and ammonia
How is ammonia detoxified?
Deamination
What happens in deamination?
Excess amino acids is broken down into ammonia and keto acid
What is deamination?
Removal of NH2
What happens after deamination?
Ammonia is converted to urea and water by the ornathine cycle.
Keto acid is converted to ATP by respiration
What is NH3?
Ammonia
What happens in the ornithine cycle?
Ornithine > Citrulline > Arginine > Ornithine
NH3 + CO2 > H2O) (NH3 > H2O) ( H20 > Urea
What is the simple equation for ornithine cycle?
H20 + NH3 + CO2 > 2H2O + CO (NH2)2
Why is ammonia detoxified?
Cannot store excess amino acids.
Ammonia to toxic for body.
ATP is a useful by product.
What is CO (NH2)2?
Urea
Why can fish excrete ammonia?
Plenty of water to dilute the ammonia.
Why can uric acid be stored in eggs by reptiles?
Uric acid has a low toxicity.
Won’t harm the egg
Why is alcohol part of our metabolsim?
ATP is produced
How is alcohol detoxified by the liver?
Ethanol > Ethanal > Ethanoic Acid > Ethabnate > Acetyl Co A
+( NAD > NADH) between ethanol and ethanol and ethanal and ethanoic acid
What is the consequence of alcohol abuse?
Fatty liver
Hepatitis
Cirrhosis
