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Radiation Oncology Test Prep > Functional Classification of Tumor Oncogenes > Flashcards

Functional Classification of Tumor Oncogenes Flashcards

1
Q

Growth Factors

A 
PDGF
EGF
ILGF-1
VEGF
TGF-b
IL-2
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2
Q

Growth Factor Receptors

A 
PDGFR (PDGF receptor)
EGFR, erbB-1 (EGF receptor)
ILGF-1R (ILGF-1 receptor)
met (hepatocyte growth factor receptor)
neu/erbB-2 (Heregulin receptor)
Kit (stem cell factor receptor)
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3
Q

Protein kinases

A

bcr-abl (tyrosine kinase)
src (tyrosine kinase)
raf/mil (serine-threonine kinase)
mos (serine-threonine kinase)

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4
Q

G-protein signal transducers

A

H-ras (GTPase)
K-ras (GTPase)
N-ras (GTPase)

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5
Q

Nuclear Proteins

A 
(ALL are transcription factors)
ets
fos
jun
myb
myc
rel
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Radiation Oncology Test Prep (4 decks)

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