Functional bowel disorders Flashcards
Define functional bowel disorders
- No detectable pathology
- Related to gut function
- “software faults”
- Good long term prognosis
Give some examples of functional bowel disorders
- Oesophageal spasm
- Non-ulcer dyspepsia (NUD)
- Biliary dyskinesia
- Irritable bowel syndrome
- Slow transit constipation
- Drug related effects
Understand the impact of functional bowel disorders and the role of psychological factors
- Very common cause of initial and return medical consultations
- Large impact on quality of life
- Large cause of work absences
- Psychological factors are important
- Not associated with the development of a serious pathology
What is non-ulcer dyspepsia?
- Dyspeptic type pain
- No ulcer on endoscopy (H. pylori status varies
What is non-ulcer dyspepsia caused by?
probably not a single disease
- Reflux
- Low grade duodenal ulceration
- Delayed gastric emptying
- Irritable bowel syndrome
How do you diagnose non-ulcer dyspepsia?
- Careful History and Examination
- Family History - Gastric Cancer rare in those under 45 years
- H. pylori status
- Alarm symptoms
How do you treat non-ulcer dyspepsia?
- If all negative: Treat symptomatically
- If H. pylori positive: Eradication therapy
- If Doubt: Endoscopy
What is nausea?
The sensation of feeling sick
What is retching?
- Dry heaves
- Antrum contracts, glottis closed
What is vomiting?
Contents expelled
What are the sympathetic and Vagal components of vomiting and nausea?
- Vomiting Centre (may not exist as entity)
- Chemoreceptor Trigger Zone (CTZ)
- Receptors for opiates
- Digoxin
- Chemotherapy
- Uraemia
What would the history of nausea and vomiting be?
Length of time after food - Immediate - Psychogenic - 1 hour or more - Pyloric obstruction - Motility disorders ~ Diabetes ~ Post gastrectomy - 12 hours - Obstruction etc
What are the functional causes of nausea and vomiting
- Drugs
- Pregnancy
- Migraine
- Cyclical Vomiting Syndrome
- Onset often in childhood
- Recurrent episodes 2-3 x year – 2-3 x month - Alcohol
What is psychogenic vomiting?
- Often young women
- Often for years
- May have no preceding nausea
- May be self induced (overlap with bulimia)
- Appetite usually not disturbed but may lose weight
- Often stops shortly after admission
What are alarm symptoms?
- Age > 50
- Short symptom history
- Unintentional weight loss
- Nocturnal symptoms
- Male sex
- Family history of bowel/ ovarian cancer
- Anaemia
- Rectal bleeding
- Recent antibiotic use
- Abdominal mass