function of the nephron Flashcards

1
Q

where does ulterfiltration occour

A

the glomerulas

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2
Q

what is the artriole that takes blood into the glomerulas called

A

the efferent artriole

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3
Q

what is the glomerulas comprised of

A

capillaries

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4
Q

what are the glomerular capillaries made up of

A

epithelial cells with pores between them

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5
Q

what is formed in the glomerulas that allows ulterfiltration to occour

A

hydrostatic pressure is formed

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6
Q

how is this hydrostatic presure formed

A

the differance in size between the afferent artriole wich has a smaller diameter compared to the efferent atriole.

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7
Q

what does this hydrostatic pressure do

A

forces small water glucose and mineral ions into bomans capsual forming glomerular filtrate

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8
Q

what is the water, glucose and mineral ions known as when pushed out of pores

A

glomerular filtrate

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9
Q

what remains in the blood stream

A

blood cells and protiens

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10
Q

why do they reamain in the blood stream

A

they are too large

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11
Q

what do these large cells leave via

A

the efferent atriole

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12
Q

what occours after uterfiltration

A

selective reabsorbtion

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13
Q

where does selective reabsorbtion happen

A

the proximal convoluted tubual

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14
Q

what absorbs glucose and aa into the blood

A

epithelial cells in the lining of the pct

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15
Q

what makes the epithelial cells suited for their absorbtion

A

microvilli - provide large SA
mitochondria - provide lots of energy for active transport and co transport

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16
Q

what is the mitochondria in the epithelia cells used for

A

active and co - transport

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17
Q

describe the process of reabsorbtion

A

sodium ions actively transported into the blood lowering the sodium con in epithelial cells.
sodium ions diffuse down con-gradient into cells via facilitated diffusion with the use of a carrier protein.
travels from lumen of pct into epithelial cells surrounding it.
carrier protiens contransport molcules such as glucose and aa into epithelial cells
co-transported molecules diffuse dwn a conc gradient into the blood.

18
Q

how do glucose molecules move into epethillial cells

A

via co-traqnsport with sodium ions through a carrier protien

19
Q

how do sodium ions move into the epithellial cell

A

facillitated diffusion

20
Q

how are the co-transported molecules transported into the blood stream

A

via diffusion down a conc gradient wich is alwas maintained as blood constantly moves away

21
Q

how is ultra filtration resisted out of the glomerulas

A

cappillary epithelial cells
epithelila cells of renal capsual

22
Q

what is esential for selective reabsorbtion in terms of establishing conditions

A

maintaining the gradient of sodium ions

23
Q

what miantains the gradient of sodium ions

A

loop of henle

24
Q

what are the two regions in the loop of henle

A

descending limb
ascending limb

25
Q

what is the differance between the ascending and descending loop

A

descending lopp is permiable to water
ascending loop has thicker walls so is not

26
Q

why is the ascending loop imperable to water

A

because it has thicker walls

27
Q

what happens in the ascending loop of henely

A

sodium ions actively transported out into intertitial space

28
Q

what does the active transport of na ions out of ascending loop mena

A

lowers water potential outside

29
Q

due to the low water potential outside loop of henle what happens

A

water moves out of descending loop into the surrounding blood capillaries wich is hopw water enters the blood

30
Q

where else does water go when it moves out os descending limb

A

interstitial space

31
Q

what is the concentration at the bottom of the loop of henle

A

high conc of na+ ions becuase most water has moved out via desceding loop, this means that na+ ions can easily diffuse out into interstitial space

32
Q

why is their a high conc of na ions at the bottom of loop of henle

A

because most water has moved out via descending loop

33
Q

what does this high conc of sodium ions mean

A

sodium can easily diffuses out into interstitial space

34
Q

what changes that makes na+ ions move out of ascending loop via activetransport

A

as their is a large amount of na+ ions at the bottom of the loop of henle they can easliy move out via diffusion but as more move out the conc of na+ ions left is lower so they have to move out via active transport

35
Q

what does the movment of the na+ ions out of the ascending loop result in

A

a filtrate with a high water potential

36
Q

why does it result in a filtrate with a high water potential

A

as water is unable to move out in the ascending loop due to it’s thick walls

37
Q

after movement out of loop of henle where does filtrate go

A

collecting duct

38
Q

what happens at the collecting duct

A

water moves out via osmosis into blood capillaries

39
Q

what does the osmosis of water out of collecting duct mean

A

lowered water potential

40
Q

what continues to allow osmosis in collecting duct even when their is a low water potential in collecting duct

A

water potential of filtrate is lower but so is water potential of interstilita space due to the constant movement of blood taking water away so water keeps moving out of collecting duct. this is an example of the counter current model

41
Q

why is the water potential of interstial space still lower than that in collecting duct

A

due to constant movement of water away bu the blood capillaries