Full Blood Count Flashcards
1
Q
What would an FBC show you?
A
- Hb
- MCV
- Reticulocyte count
- RCC
- Haematocrit/PCV
- MCH
- MCHC
- WCC + platelet count
2
Q
What are examples of microcytic anaemia?
A
- Siberoblastic
- Iron deficiency
- Thalassaemia
3
Q
What are examples of normocytic anaemia?
A
- Acute blood loss
- Haemolytic anaemia
- Sickle cell
4
Q
What are examples of megaloblastic macrocytic anaemia?
A
- Decreased B12
- Decreased folate
5
Q
What are examples of non-megaloblastic macrocytic anaemia?
A
- Alcohol
- Reticulocytosis
- Liver disease
- Pregnancy
6
Q
What do WBC’s tell you?
A
- High neutrophils - bacterial infection, inflammation, corticosteroids, malignancy
- High lymphocytes - viral infection, chronic infections, lymphoma
- High monocytes - bacterial infection, autoimmune diseases
- High eosinophils - allergy, parasite infections
7
Q
What are blood tests for specific causes?
A
- Haematinics: B12, folate and ferritin
- Iron
- TFTs
- Bilirubin (unconjugated bilirubin is raised in haemolysis)
- Blood film +/- bone marrow biopsy (if bone marrow cause/sideroblastic anaemia suspected)
- Hb electrophoresis
8
Q
What are the inherited causes for haemolytic anaemia?
A
- Haemoglobinopathies: sickle cell, thalassaemia
- Membrane defects: hereditary spherocytosis, elliptocytosis
- Enzyme defects: G6PD deficiency, pyruvate kinase deficiency
