Ftct Flashcards
What is the biochemical reaction of Moraxella catarrhalis?
Oxidase positive, catalase positive, non sugar fermenter, produce beta-lactamase, DNase positive
Oxidase positive, catalase positive, non sugar fermenter, produce beta-lactamase, DNase positive
What is the morphology of Pseudomonas aeruginosa?
Gram-negative rods
Gram-negative rods
Which of the following is a characteristic of Pseudomonas aeruginosa culture?
Gives greenish colour to nutrient agar with sweet grape-like fruity odor
Gives greenish colour to nutrient agar with sweet grape-like fruity odor
What is the biochemical reaction of Pseudomonas aeruginosa?
Do not ferment carbohydrates
Do not ferment carbohydrates
Which of the following is a virulence factor of Pseudomonas aeruginosa?
Pyocyanin
Pyocyanin
In which conditions does Pseudomonas aeruginosa commonly cause infection?
Disruption of mucous membrane and skin, usage of intravenous or urinary catheters, neutropenia
Disruption of mucous membrane and skin, usage of intravenous or urinary catheters, neutropenia
Which of the following is a clinical disease caused by Pseudomonas aeruginosa?
Infection of wounds and burns
Infection of wounds and burns
How is Pseudomonas aeruginosa diagnosed in the laboratory?
Specimen: skin lesions, pus, urine, blood, spinal fluid, sputum. Culture: ??? Biochemical reaction: ???
Specimen: skin lesions, pus, urine, blood, spinal fluid, sputum. Culture: ??? Biochemical reaction: ???
What is the treatment for Pseudomonas aeruginosa infection?
Combined antibiotic therapy with aminoglycoside, antipseudomonal B-lactam or a quinolone
Combined antibiotic therapy with aminoglycoside, antipseudomonal B-lactam or a quinolone
What is the morphology of Moraxella catarrhalis?
Gram-negative cocci or diplococci
Gram-negative cocci or diplococci
Which of the following is a characteristic of Moraxella catarrhalis culture?
Grayish-white colonies which scoot across the agar without disruption when pushed by loop
Grayish-white colonies which scoot across the agar without disruption when pushed by loop
How is Bacillus anthracis diagnosed in the laboratory?
Specimens: fluid or pus from local lesion, blood, or sputum. Smears: long chains of large gram-positive rods without spores can be seen. Culture: nonhemolytic gray colonies with dry surface on blood agar plates. Identification: made in a reference lab by direct fluorescent Ab test against capsular polypeptide or PCR test.
What is the treatment for Bacillus anthracis infection?
Multi drug therapy with ciprofloxacin, rifampin and vancomycin
What is the morphology of Pseudomonas aeruginosa?
Gram-negative rods
What is the color of Pseudomonas aeruginosa on nutrient agar?
Greenish
What is the temperature range for the growth of Pseudomonas aeruginosa?
37°C to 42°C
What are the exopigments produced by Pseudomonas aeruginosa?
Pyocyanin and Pyoverdin
What is the biochemical reaction of Pseudomonas aeruginosa for carbohydrate fermentation?
Do not ferment carbohydrates
What is the virulence factor of Pseudomonas aeruginosa that causes tissue necrosis and disrupts protein synthesis?
Exotoxin A
In which environments is Pseudomonas aeruginosa commonly present?
Moist environments in hospitals
What are the predisposing factors for Pseudomonas aeruginosa infection?
Disruption of mucous membrane and skin, usage of intravenous or urinary catheters, neutropenia
Which clinical diseases can be caused by Pseudomonas aeruginosa?
Infection of wounds and burns, ear infections, skin and nail infections, chronic otitis media, meningitis, osteochondritis of the foot, pulmonary infection, urinary tract infection, tracheobronchitis, gastrointestinal infection, necrotizing pneumonia in CF patients, sepsis, eye infections
Which clinical diseases can be caused by Pseudomonas aeruginosa?
Infection of wounds and burns, ear infections, skin and nail infections, chronic otitis media, meningitis, osteochondritis of the foot, pulmonary infection, urinary tract infection, tracheobronchitis, gastrointestinal infection, necrotizing pneumonia in CF patients, sepsis, eye infections
Example sentence: Pseudomonas aeruginosa can cause a variety of infections such as wound infections and urinary tract infections.
What is the treatment for Pseudomonas aeruginosa infection?
Combined antibiotic therapy with aminoglycoside, antipseudomonal B-lactam, or a quinolone
Which of the following is a clinical infection caused by Moraxella catarrhalis?
Otitis media
How is Moraxella catarrhalis diagnosed in the laboratory?
Sample: pus, sputum, CSF. Smear: Gram negative diplococci. Culture: Smooth grayish-white colour. Biochemical reaction: Oxidase positive, catalase positive, non sugar fermenter, produce beta-lactamase, DNase positive
What is the treatment for Moraxella catarrhalis infection?
Fluoroquinolones, most second and third generation cephalosporins, erythromycin, and amoxicillin-clavulanate
What is the morphology of Bacillus anthracis?
Large gram-positive rods, have square ends, arranged in long chains
Which of the following is a characteristic of Bacillus anthracis culture?
Nonhemolytic gray-white colonies with dry surface on blood agar plates
What is the pathogenesis of Bacillus anthracis?
Primarily a disease of herbivores; humans and animals are equally affected. In humans and animals, portal of entry is mouth and GI tract. In humans and animals, scratches in the skin, ingestion or inhalation lead to infection.
What is the pathogenesis of Bacillus anthracis?
Primarily a disease of herbivores; humans are rarely affected. In animals, portal of entry is mouth and GI tract. In humans, scratches in the skin, ingestion or inhalation lead to infection.
Example sentence: An individual may become infected with Bacillus anthracis after inhaling spores while working with contaminated animal hides.
Which of the following is a clinical disease caused by Bacillus anthracis?
Inhalation anthrax (wool-sorters’ disease)
Example sentence: Inhalation anthrax is a severe form of the disease that can result in high mortality rates if not promptly treated.