Ftct Flashcards

1
Q

What is the biochemical reaction of Moraxella catarrhalis?

A

Oxidase positive, catalase positive, non sugar fermenter, produce beta-lactamase, DNase positive

Oxidase positive, catalase positive, non sugar fermenter, produce beta-lactamase, DNase positive

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2
Q

What is the morphology of Pseudomonas aeruginosa?

A

Gram-negative rods

Gram-negative rods

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3
Q

Which of the following is a characteristic of Pseudomonas aeruginosa culture?

A

Gives greenish colour to nutrient agar with sweet grape-like fruity odor

Gives greenish colour to nutrient agar with sweet grape-like fruity odor

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4
Q

What is the biochemical reaction of Pseudomonas aeruginosa?

A

Do not ferment carbohydrates

Do not ferment carbohydrates

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5
Q

Which of the following is a virulence factor of Pseudomonas aeruginosa?

A

Pyocyanin

Pyocyanin

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6
Q

In which conditions does Pseudomonas aeruginosa commonly cause infection?

A

Disruption of mucous membrane and skin, usage of intravenous or urinary catheters, neutropenia

Disruption of mucous membrane and skin, usage of intravenous or urinary catheters, neutropenia

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7
Q

Which of the following is a clinical disease caused by Pseudomonas aeruginosa?

A

Infection of wounds and burns

Infection of wounds and burns

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8
Q

How is Pseudomonas aeruginosa diagnosed in the laboratory?

A

Specimen: skin lesions, pus, urine, blood, spinal fluid, sputum. Culture: ??? Biochemical reaction: ???

Specimen: skin lesions, pus, urine, blood, spinal fluid, sputum. Culture: ??? Biochemical reaction: ???

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9
Q

What is the treatment for Pseudomonas aeruginosa infection?

A

Combined antibiotic therapy with aminoglycoside, antipseudomonal B-lactam or a quinolone

Combined antibiotic therapy with aminoglycoside, antipseudomonal B-lactam or a quinolone

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10
Q

What is the morphology of Moraxella catarrhalis?

A

Gram-negative cocci or diplococci

Gram-negative cocci or diplococci

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11
Q

Which of the following is a characteristic of Moraxella catarrhalis culture?

A

Grayish-white colonies which scoot across the agar without disruption when pushed by loop

Grayish-white colonies which scoot across the agar without disruption when pushed by loop

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12
Q

How is Bacillus anthracis diagnosed in the laboratory?

A

Specimens: fluid or pus from local lesion, blood, or sputum. Smears: long chains of large gram-positive rods without spores can be seen. Culture: nonhemolytic gray colonies with dry surface on blood agar plates. Identification: made in a reference lab by direct fluorescent Ab test against capsular polypeptide or PCR test.

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13
Q

What is the treatment for Bacillus anthracis infection?

A

Multi drug therapy with ciprofloxacin, rifampin and vancomycin

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14
Q

What is the morphology of Pseudomonas aeruginosa?

A

Gram-negative rods

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15
Q

What is the color of Pseudomonas aeruginosa on nutrient agar?

A

Greenish

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16
Q

What is the temperature range for the growth of Pseudomonas aeruginosa?

A

37°C to 42°C

17
Q

What are the exopigments produced by Pseudomonas aeruginosa?

A

Pyocyanin and Pyoverdin

18
Q

What is the biochemical reaction of Pseudomonas aeruginosa for carbohydrate fermentation?

A

Do not ferment carbohydrates

19
Q

What is the virulence factor of Pseudomonas aeruginosa that causes tissue necrosis and disrupts protein synthesis?

A

Exotoxin A

20
Q

In which environments is Pseudomonas aeruginosa commonly present?

A

Moist environments in hospitals

21
Q

What are the predisposing factors for Pseudomonas aeruginosa infection?

A

Disruption of mucous membrane and skin, usage of intravenous or urinary catheters, neutropenia

22
Q

Which clinical diseases can be caused by Pseudomonas aeruginosa?

A

Infection of wounds and burns, ear infections, skin and nail infections, chronic otitis media, meningitis, osteochondritis of the foot, pulmonary infection, urinary tract infection, tracheobronchitis, gastrointestinal infection, necrotizing pneumonia in CF patients, sepsis, eye infections

23
Q

Which clinical diseases can be caused by Pseudomonas aeruginosa?

A

Infection of wounds and burns, ear infections, skin and nail infections, chronic otitis media, meningitis, osteochondritis of the foot, pulmonary infection, urinary tract infection, tracheobronchitis, gastrointestinal infection, necrotizing pneumonia in CF patients, sepsis, eye infections

Example sentence: Pseudomonas aeruginosa can cause a variety of infections such as wound infections and urinary tract infections.

24
Q

What is the treatment for Pseudomonas aeruginosa infection?

A

Combined antibiotic therapy with aminoglycoside, antipseudomonal B-lactam, or a quinolone

25
Q

Which of the following is a clinical infection caused by Moraxella catarrhalis?

A

Otitis media

26
Q

How is Moraxella catarrhalis diagnosed in the laboratory?

A

Sample: pus, sputum, CSF. Smear: Gram negative diplococci. Culture: Smooth grayish-white colour. Biochemical reaction: Oxidase positive, catalase positive, non sugar fermenter, produce beta-lactamase, DNase positive

27
Q

What is the treatment for Moraxella catarrhalis infection?

A

Fluoroquinolones, most second and third generation cephalosporins, erythromycin, and amoxicillin-clavulanate

28
Q

What is the morphology of Bacillus anthracis?

A

Large gram-positive rods, have square ends, arranged in long chains

29
Q

Which of the following is a characteristic of Bacillus anthracis culture?

A

Nonhemolytic gray-white colonies with dry surface on blood agar plates

30
Q

What is the pathogenesis of Bacillus anthracis?

A

Primarily a disease of herbivores; humans and animals are equally affected. In humans and animals, portal of entry is mouth and GI tract. In humans and animals, scratches in the skin, ingestion or inhalation lead to infection.

31
Q

What is the pathogenesis of Bacillus anthracis?

A

Primarily a disease of herbivores; humans are rarely affected. In animals, portal of entry is mouth and GI tract. In humans, scratches in the skin, ingestion or inhalation lead to infection.

Example sentence: An individual may become infected with Bacillus anthracis after inhaling spores while working with contaminated animal hides.

32
Q

Which of the following is a clinical disease caused by Bacillus anthracis?

A

Inhalation anthrax (wool-sorters’ disease)

Example sentence: Inhalation anthrax is a severe form of the disease that can result in high mortality rates if not promptly treated.