Frontotemporal Dementia and Alzheimer's Disease

Question 1

What is the definition of dementia

Answer 1

A persistent (>6 months) cognitive deterioration (>_2domains) severe enough to affect activities in daily life (ADL)

Question 2

Give examples of cognitive functions that are commonly impaired in dementia patients

Answer 2

• memory
• problem solving, logical thinking
• visuospatial function
• language
• executive functions

Question 3

Give example of behavioral and psycological symptoms of dementia (BPSD)

Answer 3

Depression, Anxiety, Agitation, Hallucinations etc

Question 4

Give example of a couple of basic ADL (activities in daily life) that are impaired in dementia patients

Answer 4

• dressing
• taking a shower
• eating and drinking
• visit the toilet
• walking indoors

Question 5

Give example of a couple of complex ADL (activities in daily life) that are impaired in dementia patients

Answer 5

Cleaning 
Shopping for food 
Paying the bills 
Cooking 
Biking 
Walking outdoors
Taking your medication

Question 6

How long is the AD disease progression?

Answer 6

from 3-20 years

Question 7

In a MRI scan, what is a common sign of AD?

Answer 7

Brain atrophy more specifically medial temporal atrophy

Question 8

Name the three subtypes of FTD

Answer 8

1. Behavioral variant
2. Progressive non-fluent aphasia (can also be classified as a subgroup of primary progressive aphasia)
3. Semantic dementia (can also be classified as a subgroup of primary progressive aphasia)

Question 9

Name criteria for probable FTD

Answer 9

should have 3 out of 6:

• disinhibition
• apathy or inertia
• loss of sympathy or empathy
• perseverations
• hyperorality/diertary changes
• executive deficits&raquo_space; memory loss

+ functional decline (dementia) and frontal/anterior temporal atrophy or hypometabolism

Question 10

How long is the FTD disease progression?

Answer 10

2-12 years