From Formative Flashcards

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1
Q

what carries out vitamin D metabolism in the skin?

A

keratinocytes

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2
Q

where is energy stored in the skin?

A

subcutaneous fat

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3
Q

where does epidermal proliferation happen in the skin?

A

basal cells

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4
Q

are topical steroids vasodilative or vasoconstrictive?

A

vasoconstrictive

also lipophilic, anti-proliferative and anti-inflammatory

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5
Q

which enzyme is deficient in Erythropoietic protoporphyria?

A

ferrocheletase

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6
Q

how thick is the granular layer?

A

2-3 cells thick

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7
Q

where are fibroblasts found in the skin?

A

in the dermis

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8
Q

which glands Moisten palms/soles for grip?

A

eccrine glands

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9
Q

which glands maintain the skin barrier?

A

sebaceous glands

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10
Q

where are odland bodies found?

A

in the granular layer

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11
Q

what is associated with highly virulent strains of Staph. aureus causing necrolytic skin infections?

A

PVL (Panton valentine leukocidin) cytotoxin

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12
Q

where are hemi-desmosomes in the skin?

A

found within the dermo-epidermal junction

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13
Q

child crying and rubs at skin when playing outside?

A

Erythropoietic protoporphyria

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14
Q

what is prevalence?

A

the proportion of a population affected by a disease at any given time

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15
Q

which glands are the commonest sweat glands on the face?

A

eccrine sweat glands

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16
Q

which glands play a role in temperature regulation?

A

eccrine sweat glands

17
Q

what cytotoxin causes damage to the host indirectly?

A

modulins

18
Q

which cytotoxin enables the organism to avoid host defence mechanisms?

A

impedins

19
Q

which cytotoxin enables the organism to invade a host tissue?

A

invasin

20
Q

which enzyme is deficient in acute intermittent porphyria?

A

Porphobilinogen deaminase

21
Q
A