Friday_1 Flashcards
Is paroxetine on the Beers List?
Yes, risk of mild anticholinergic ADRs, low BP
Name 2 ADRS from paroxetine that are more significant than other SSRIs
Sedation, Weight Gain
If you only have Protein/creatinine ratio how can you convert to albumin/creatinine ration?
“Less than 142 mg/g then probably are A1
Between 142 mg/g to 660 – A2
Above 660 – A3”
What are the risks as albuminuria increases?
Higher albuminuria, higher risk for AKI, progression of CKD, ESRD, higher risk of CVD
Name 3 indications for partoxetine
Depression, anxiety, PTSD, OCD, hot flashes
Describe the dual action of albuterol and ipratropium
Albuterol kicks in earlier, doesn’t last long vs ipratropium – longer to start 20m lasts longer
As SABA wears off, SAMA sticks around
Time of bronchodilation is extended by using both products
What is the relationship between GFR and HCTZ?
Lower GFR, lower efficacy of HCTZ. Under GFR of 45 don’t use HCTZ so much
Chlorthalidone use all the way down to GFR of 30
Add loop in CKD 4
Which GLP1s have highest efficacy for weight loss?
" Semaglutide Liraglutide Dulaglutide Exenatide Lixasenatide"
What is a BBW for GLP1 agonists
History of Medullary thyroid cancer (people usually have papullary)
What are the considerations in ticagralor for post PCI?
It’s BID – is this too hard for you to take? 10% have adenosine mediated dyspnea. What’s the co-pay, can they afford it? $400 a month
Zantac
Ranitidine
Verapamil medication class
Non-dihydropyridine CCB
Name 3 uses for verapamil
Afib, HTN, Angina, Cluster Headache Prophylaxis
What are the ADA A1c goals for older adults?
Healthy adult 7.0 to 7.5%, complex patient, less than 8% and poor health has no goal
Losartan is indicated for…
HTN, PostMI, CHF, Proteinuria, lowering Uric Acid
Losartan monitoring parameters
K, BP, Scr
What are counseling points for starting beta blockers?
These medications will help you live longer and help you feel better. Lower BP and Lower HR, so heart has to do less work, allowing it to recover.Get doses as high as we can get them. Higher the doses, the longer you will live. Only care about if you feel dizzy or light-headed. BP number is not important.
Are brand and generic levothyroxine doses safe and equivalent
Yes. But you should stick to one manufacturer if possible
What’s a counseling point on levothyroixine
Take the same time, same way every day.
What’s the half life of levothyroxine?
7 days
What are the ingredients in Armour Thyroid?
Desiccated animal thyroid. Mix of T4 and T3. FDA unapproved but widely used drug
What is the goal dosing of levothryroxine?
1.5 mcg per kg per day – average is 125mcg per day. But varies widely