Frailty, Sarcopenia and Immobility Flashcards

1
Q

What is frailty?

A

A medical syndrome in which an individual has decreased strength, endurance and physiological function, this increases their risk of dependency and death

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2
Q

What is the difference between sarcopenia and cachexia?

A

Sarcopenia is age related loss of muscle mass. Cachexia is loss a metabolic condition resulting in loss of weight and muscle mass

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3
Q

What are the three criteria that make up sarcopenia and how are they measured?

A

Low muscle mass
Poor physical performance (timed walk test)
Poor muscle strength (grip test)
If all three are present then severe sarcopenia, if just low muscle mass then pre-sarcopenia

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4
Q

How do geriatricians diagnose frailty?

A

With the comprehensive geriatric assessment

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5
Q

What are the two methods that non geriatricians can use to diagnose frailty?

A

Electronic frailty index - computer calculated

Edmonton Frail Scale - questionnaire of physical function and cognition

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6
Q

How is sarcopenia diagnosed?

A

First gait speed is measured:

  • if it is less than 0.8m/s then imaging is used (usually DEXA) to diagnose low muscle mass
  • if it is greater than 0.8m/s then grip strength is tested and imaging is only used if this is low
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7
Q

What is the management for frailty and sarcopenia?

A

Both reversible conditions:

  • exercise intervention - particularly involving strength work
  • Nutrition involving protein or amino acid supplementation
  • Comprehensive geriatric assessment - demonstrated to reverse frailty and improve outcomes
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8
Q

What are the main causes of immobility?

A
Previous fall - injury or fear prevents mobilisation
Osteoarthritis
Parkinsons
Stroke
Visual impairment
Chronic Cardiorespiratory disease
Feet or footwear
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9
Q

How is immobility managed?

A

It is a multidisciplinary approach
Need to identify the cause of the immobility and treat it
Requires physio and occupational therapist input

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10
Q

What is the WHO definition of osteoporosis?

A

This is 2.5 standard deviations (SD) below the bone mineral density of the general population

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11
Q

What are the risk factors for osteoporosis?

A
Female
Increased Age
Corticosteroid use
smoking
alcohol
Low BMI
Family history
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12
Q

What screening tool should be used for osteoporosis, what does it work out?

A

Should use frax or q fracture

Generate the 10 year risk of patients developing fragility fractures

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13
Q

How is actual bone mineral density calculated? what results must be treated?

A

Using DEXA scanning of hips and lumbar spine

A T score of less than -2.5 should be treated with bisphosphonates

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14
Q

What does a t score of -1 to -2.5 suggest vs a score of less than -2.5?

A

This shows osteopenia and less than -2.5 shows osteoporosis

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15
Q

What are some of the causes for a patient presenting ‘off legs’?

A

Vitamin CDE
Vascular - silent MI or DVT
Infective - UTI or LRTI
Trauma - Hip fracture - could be non traumatic
Autoimmune - not really
Metabolic - hypo/hypernatraemia, hypercalcaemia common causes of lethargy and confusion
Inflammatory - Pressure sores could stop them getting out of bed
Neoplastic - cause lethargy and cachexia, if deteriorating for a while this could be the cause
Congeital - no
Degenerative - OA
Endocrine - addisons can cause low BP and lethargy

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16
Q

What is the fragility phenotype model?

A

Five criteria to identify frailty:

  • Weight loss
  • Slowness
  • Weakness
  • Low physical activity
  • Exhaustion