Formulations and Dosage Calculations

Question 1

Aqueous solutions, Syrups and Elixars have a ______ rate of absorption

Answer 1

Fast

Question 2

Compressed tablets, enteric-coated tablets and complex forms have a ______ rate of absorption

Answer 2

Slow

Question 3

The risk of bioavailability problems of Aqueous solutions, Syrups and Elixars is _______

Answer 3

Low

Question 4

The risk of bioavailability problems of Compressed tablets, enteric-coated tablets and complex forms is _______

Answer 4

High

Question 5

Medicine plus lots of other ngredients

Answer 5

Tablet

Question 6

Encapsulated i.e. Omperazole

Answer 6

Capsules

Question 7

Bioavailability

Answer 7

The fraction of drug that is absorbed

Question 8

Why do some medicines have coatings?

Answer 8

So that the drug is only released in certain parts of the GI tract when you want to release them

Question 9

Bioequivalence

Answer 9

Both drugs have an identical rate and extent of absorption

Question 10

Bioequivalence is assessed by 3 things. What are they?

Answer 10

1. Time to peak plasma level (tmax)
2. Peak plasma level (Cmax)
3. Bioavailability (F)

Question 11

Cmax

Answer 11

Maximum plasma concentration (highest peak on graph)

Question 12

When do side effects usually occur?

Answer 12

At Cmax

Question 13

Which type of preparation is formulated to resist dissolution and may be used to reduce rate of absorption and prolong action

Answer 13

Modified or sustained release preparations

Question 14

Another term for formulation is _____

Answer 14

Preparation

Question 15

Oramorph

Answer 15

Oral suspension for immediate pain relief

Question 16

Morphogesic SR

Answer 16

Sustained release and provides 12 hourly pain relief

Question 17

Immediate release preparations are associated with ______

Answer 17

Increased cardiac events