Formulas Flashcards
maximum allowable blood loss
(EBV x (Hct starting- Hct target))/ Hct starting
Law of Laplace
pressure= (2 x tension) / radius
PVR
((mPAP-PAOP)/CO) x 80
Norm= 150-200
SVR
((MAP-CVP)/CO) x 80
Norm= 800-1500
metabolic equivalent
metabolic rate of specific physical activity/metabolic rate at rest
trans pulmonary pressure
alveolar pressure-intraplural pressure
Alveolar ventilation
(TV- dead space) x RR or CO2 production/PaCO2
minute ventilation (VE)
TV x RR or Vt x RR
dead space to tidal volume ration (Vd/Vt)
0.33 in SV patient, 0.5 in mechanical ventilation
PaCO2-PeCO2)/PaCO2 (PeCo2=partial pressure of CO2 in exhaled gas, not the same as ETCO2
Law of Laplace cylinder
tension=pressure x radius
Law of Laplace sphere
tension = (pressure x radius)/2
Alveolar oxygen (PAO2)
FiO2 x (Pb - PH2O) - (PaCO2 / RQ) PH2O= humidity of inhaled gas, assumed to be 47 mmHg RQ= respiratory quotient, assumed to be 0.8 Normal 105.98 mmHg
Can estimate FiO2 x 6
Respiratory quotient
Co2 production/O2 consuption= 200 mL/min / 250 mL/min =0.8
>1= lipogenesis (overfeeding)
<1= lipolysis (Starvation)
Estimation of shunt %
Shunt increases 1% for every 20 mmHg A-a gradient
TV
FRC
VC
TV= 6-8 mL/kg
FRC= 35 mL/kg
VC= 65-75 mL/kg
calculated with ideal body weight
CaO2
O2 carrying capacity
(1.34 x SaO2 x Hgb) + (PaO2 x 0.003)
Normally 20 ml O2/dL
DO2
O2 delivery
CaO2 x CO x 10
Normally about 1000 mL O2/min
Normal H and H values
women 13 and 39
men 15 and 45
VO2
O2 consumption CO x (CaO2-CvO2) x 10
3.5 mL/kg/min
250 mL/min in 70 kg patient
Normal P50 O2
Where hgb 50% saturated by O2
26.5 mmHg
Lower= L
Higher= R
Bicarb reaction in blood
70%
H2O + CO2 H2CO3(carbonic acid) H+ + HCO3-
Need carbonic anhydrase for first reaction
H+ buffered by Hmg
HCO3 transported in plasma, Cl- goes into cell
Co2 bound to hemoglobin
23%
R-NH2 + CO2 RNH-CO2- + H+
Co2 dissolved in plasma
7%
solubility coefficient 0.067 mL/dL/mmHg
Vd/Vt
2ml/kg / 6mL/kg (normally 0.33)
increases to 0.5 in mechanical ventilation
FiO2
((Air flow rate x 21) + (O2 flow rate x 100)) / Total flow rate
Tidal volume with fresh gas coupling
Vt on ventilator - FGF during inspiration - vol lost to compliance
- Convert fresh gas flow from L/min to mL/min
- Multiple by FGF by the percentage of time in inspiration (1:2 IE= 33.33%)
- Divide 2 by RR.
- Add set Vt to 3.
Most new ventilators decouple so this does not apply
Reynold’s number
(Density x diameter x velocity)/viscosity
Re<2000= laminar flow (dependent on gas viscosity)
Re > 4000= turbulent flow (depending on gas density)
2000-4000= transitional flow
Volume lost to circuit
Circuit compliance x peak pressure
Some of Vt used to expand circuit
mL of liquid anesthetic agent used per hour
Vol% x FGF in L/min x 3
calculating vaporizer output at elevation
Required dial setting= (normal dial setting x 760)/ambient pressure (mmHg)
Higher altitude= higher setting
Lower altitude= lower setting
reaction of CO2 with sodalime
CO2 + H2O = H2CO3 (carbonic acid)
H2CO3 + 2 NaOH = Na2CO3 + 2 H2O + heat
Na2CO3 + Ca(OH)2 = CaCO3 (calcium carbonate) + 2 NaOH (sodium hydroxide)
Absorbent capacities
Soda lime 26L of CO2 per 100 g
Calcium hydroxide lime 10.6 L per 100g
reaction of CO2 with calcium hydroxide lime
CO2 + H2O= H2CO3
H2CO3 + Ca(OH)2 = CaCO3 + 2H2O + energy(heat)
No CO and very title compound A
Lower fire risk
Less absorbent capacity
Hydration of sodalime
13-20% by weight
Mapleson for SV and controlled ventilation
SV- A > DFE > CB
CV- DFE> BC> A
Plateau pressure
Pressure in smal airways and alveoli after tital volume is delivered
During inspiratory pause
Barotrauma risk increased with pressure > 35 cm/H2O
Static compliance= tidal volume/ (plateau pressure- PEEP)
Peak inspiratory pressure
Maximum pressure during inspiration
Dynamic compliance= tidal volume/ (PIP-PEEP)
Dysfunctional hemoglobin
Carboxyhemoglobin- absorbs 660 at same rate as oxyhemoglobin, Overestimates SpO2
Methemoglobin- absorbs 660 and 990 equally, Underestimates if > 85%
Overestimates if < 85%
SPO2
Oxygenated hgb/ (oxygenated hgb + deoxygenated hgb) X 100%
BP cuff sizing
length- long enough to wrap around 80% of arm
width- 40% circumference of patients arm
Arm position and NIBP reading
10 cm= 7.4 mmHg change
1 inch= 2 mmHg
Mixed venous O2 saturation
SvO2= SaO2- (VO2/(Q x 1.34 x Hgb x 10)) Normal= 65-75%
VO2= oxygen consumption SaO2= loading of hemoglobin in arterial blood
Need a PA cath to get blood from SVC, IVC, and coronary sinus together
Bipolar leads
I- lateral, CxA
II- inferior, RCA
III- inferior, RCA
Limb leads
AVR
AVL
Lateral
CxA
aVF
Inferior
RCA
Precordial
V1- septum, LAD V2- septum, LAD V3- anterior, LAD V4- anterior, LAD V5- lateral, CxA V6- lateral, CxA
Axis deviation
Use lead 1 and aVF
+ and += normal (between -30 and +90)
- and -= extreme R
Leads are Reaching towards each other(I down and aVF up)= R (greater than 90)
Leads are Leaving each other (I up and aVF down)= L (less than -30)
Class 1 antiarrhythmic
Na+ channel blockers
1A- quinidine, procainamide, disopyramide
Phase 0 dep, prolonged phase 3 repol
1B- lidocaine, phenytoin
Phase 0 dep, shortened phase 3 repol
1C- flea indie, propafenone
Strong phase 0 dep
Class 2 anti arrhythmic
Beta blockers
Slows phase 4 depol in SA node
Class 3 antiarrhythmic
K+ channel blockers
Amiodarone, bretylium
Prolongs phase 3 repolarization
Increased effective refractory period
Class 4 antiarrhythmic
Ca Channel blockers
Verapamil, dilt
Decreased conduction velocity through AV node
Torsades pneumonic
POINTES Phenothiazines Other meds- methadone, droperidol, haldol, zofran, halogenated agents, amiodarone, quinidine Intracranial bleed No known cause Type I antiarhythmics Electrolyte disturbances- low K, low Ca, low Mg Syndromes- Romano ward, Timothy
EEG waveforms
Beta- high frequency, low voltage, awake or light anesthesia
Alpha- medium frequency, awake but restful with eyes closed
Theta- general anesthesia and children sleeping
Delta- low frequency, GA, deep sleep, and brain injury
Definition of pulmonary hypertension
PAP > 25 mmHg
PVR
((mean PAP - PAOP) X 80) / CO
Norm= 150-250 dynes/sec/cm to the -5th power
Drugs you can give in ETT
NAVEL
Narcan, atropine, vasopressin, epi, lidocaine
Objective measures of respiratory distress
Vital capacity (mL/kg)- <15
Inspiratory force (cm/H2O)- <25
Oxygenation at 21%- PaO2 <55, A-a gradient >55
Oxygenation at 100%- PaO2 < 200, A-a gradient >450
PaCO2 >60
RR >40 or <6
Indicators of postoperative pulmonary complications in patients undergoing pulmonary surgery
Airflow: FEV1<40% of predicted
Gas exchange: DLCO < 40% of predicted
Cardiopulmonary reserve: VO2 max < 15 mL/kg/min (normal male=35-40, normal female=27-31) (if can’t climb 2 flights of stairs, this patient is at risk)
Double lumen tube placement
Male: size 39-41 fr, depth 29cm
Female: size 37-29 fr, depth 27cm
Children 8-9: 26 size
Childre >10 : 28 or 32 size
Lateral decubitus and V/Q
Nondependent- better ventilated
Dependent- better perfused
Mallampati pneumonic
PUSH
Pillars, uvula, soft palate, hard palate