Formed Elements/ Corpuscles

Question 1

Where are corpuscles originated from?

Answer 1

Hemopoietic stem cells called (Hemocytoblasts).

Question 2

Give rise to daughter cells that differentiate into various corpuscles?

Answer 2

Hemocytoblasts

Question 3

Proerythroblasts

Answer 3

Produce red blood cells.

Question 4

Megakaryoblasts

Answer 4

Produce platelets.
— Develop into megakaryocytes.

Question 5

What stimulates megakaryoblasts and is produced and released by the liver?

Answer 5

Thrombopoietin (TPO)

Question 6

What stimulates Proerythroblasts and is produced and released by the Kidneys?

Answer 6

Erythropoietin (EPO)

Question 7

If a patient is experiencing kidney failure what can be administered to help?

Answer 7

Erythropoietin (EPO)

Question 8

If a patient is going through chemotherapy what can be used?

Answer 8

Erythropoietin (EPO)

Question 9

How are formed elements/ corpuscles produced?

Answer 9

By hematopoiesis or hemopoiesis

Question 10

Where does hematopoiesis/ hemopoiesis occur?

Answer 10

In red bone marrow in post-natal life.

Question 11

What is the production of Red blood cells called?

Answer 11

Erythropoiesis

Question 12

How many days does it take for red blood cells to mature?

Answer 12

Four

Question 13

How many red blood cells are produced per second?

Answer 13

2.5 million

Question 14

How many red blood cells are destroyed per second?

Answer 14

2.5 million

Question 15

What is the main product destroyed during the destruction of RBCs?

Answer 15

Hemoglobin

Question 16

Hemoglobin is matabolized by?

Answer 16

Macrophages in liver and spleen.

Question 17

Is hemoglobin a protein?

Answer 17

Yes

Question 18

How many individual subunits make up hemoglobin?

Answer 18

Four

Question 19

Hemoglobin:

Each subunit contains a —?— molecule. And each heme contains an —?—.

Answer 19

Heme

Iron

Question 20

Hemoglobin:

What binds to the oxygen molecule.

Answer 20

Iron

Question 21

Each HB can bind up to —?— oxygens?

Answer 21

4