Formative 1 Flashcards
Which layer of the uterine wall is responsible for regenerating the tissue that is lost during menstruation?
stratum basalis
which time point does the ovaries contain the greatest number of germ cells?
7 months gestation
What is the structure called that forms from the follicle following ovulation, contains theca and granulosa derived cells, and continues to produce progesterone for about 2 weeks post-ovulation?
corpus luteum
What is the most likely embryonic explanation for two uteri?
incomplete fusion of the paramesonephric duct
In males, which structure develops to form the vas deferens?
mesonephric duct
In females, which structure develops to form the superior portion of the vagina?
paramesonephric duct
The provision of any assisted conception treatment and research using human embryos in the UK requires regulation.
What is the name of the regulatory body that provides this?
The human fertilisation and embryonic authority
Research on Human Embryos is legal in the UK.
Up to what stage can this research be performed?
Day 14
A couple attend an infertility clinic. She has had a hysterectomy as management for grade 1b endometrial cancer. All infertility investigations are normal, including normal female ovarian reserve and semen analysis.
What treatment option should be discussed?
Surrogacy
A couple attend an infertility clinic. The man had a vasectomy 5 years ago and was shown to be azoospermic following this.
What treatment option should be offered initially?
ICSI treatment with sperm obtained by surgical sperm aspiration
Which condition is the most likely cause of obstructive azoospermia?
cystic fibrosis
What proportion of couples require assessment of infertility in the UK?
1 in 6
At which stage in embryo development is embryo transfer most successful?
blastocyst
A couple present with a 5 year history of unexplained infertility. What is the best course of treatment?
IVF
A couple present to discuss assisted conception options. The man has had a vasectomy 3 years ago. What is the best option?
surgical sperm retrieval and IVF
Best course of treatment for herpes simplex infection?
Aciclovir
How long do male lice live, on average?
22 days
What proportion of patients undergoing infertility treatment are a result of male factor?
30%
Where does spermatogenesis occur in a testicle?
spermatogenesis occurs in the seminiferous tubules, the sperm is then stored in the epidermis
What structures relax in pregnancy, which could be contributing to pelvic pain?
pelvic inlet
Which structures on the foetal skull outline the vertex?
anterior and posterior fontanelles and the parietal eminences
A non-sexually active woman presents with a vaginal discharge which contains bubbles and has an offensive smell.
What is the most likely infection?
bacterial vaginosis
What proportion of women with abnormal uterine bleeding will be caused by dysfunctional uterine bleeding?
50%
Changes in the Endometrium in the luteal phase are direct effect of which hormone?
progesterone
How long does the luteal phase last in the menstrual cycle?
14 days
What information is not required when submitting an endometrial biopsy for examination?
number of pregnancies
Following a dilation and curettage for a missed miscarriage the pathology report states that this is a “complete hydatidiform mole” (CHM).
What is this at higher risk of turning in to, when compared with partial moles?
choriocarcinoma
