Formative 1

Question 1

Which layer of the uterine wall is responsible for regenerating the tissue that is lost during menstruation?

Answer 1

stratum basalis

Question 2

which time point does the ovaries contain the greatest number of germ cells?

Answer 2

7 months gestation

Question 3

What is the structure called that forms from the follicle following ovulation, contains theca and granulosa derived cells, and continues to produce progesterone for about 2 weeks post-ovulation?

Answer 3

corpus luteum

Question 4

What is the most likely embryonic explanation for two uteri?

Answer 4

incomplete fusion of the paramesonephric duct

Question 5

In males, which structure develops to form the vas deferens?

Answer 5

mesonephric duct

Question 6

In females, which structure develops to form the superior portion of the vagina?

Answer 6

paramesonephric duct

Question 7

The provision of any assisted conception treatment and research using human embryos in the UK requires regulation.

What is the name of the regulatory body that provides this?

Answer 7

The human fertilisation and embryonic authority

Question 8

Research on Human Embryos is legal in the UK.

Up to what stage can this research be performed?

Answer 8

Day 14

Question 9

A couple attend an infertility clinic. She has had a hysterectomy as management for grade 1b endometrial cancer. All infertility investigations are normal, including normal female ovarian reserve and semen analysis.

What treatment option should be discussed?

Answer 9

Surrogacy

Question 10

A couple attend an infertility clinic. The man had a vasectomy 5 years ago and was shown to be azoospermic following this.

What treatment option should be offered initially?

Answer 10

ICSI treatment with sperm obtained by surgical sperm aspiration

Question 11

Which condition is the most likely cause of obstructive azoospermia?

Answer 11

cystic fibrosis

Question 12

What proportion of couples require assessment of infertility in the UK?

Answer 12

1 in 6

Question 13

At which stage in embryo development is embryo transfer most successful?

Answer 13

blastocyst

Question 14

A couple present with a 5 year history of unexplained infertility. What is the best course of treatment?

Answer 14

IVF

Question 15

A couple present to discuss assisted conception options. The man has had a vasectomy 3 years ago. What is the best option?

Answer 15

surgical sperm retrieval and IVF

Question 16

Best course of treatment for herpes simplex infection?

Answer 16

Aciclovir

Question 17

How long do male lice live, on average?

Answer 17

22 days

Question 18

What proportion of patients undergoing infertility treatment are a result of male factor?

Answer 18

30%

Question 19

Where does spermatogenesis occur in a testicle?

Answer 19

spermatogenesis occurs in the seminiferous tubules, the sperm is then stored in the epidermis

Question 20

What structures relax in pregnancy, which could be contributing to pelvic pain?

Answer 20

pelvic inlet

Question 21

Which structures on the foetal skull outline the vertex?

Answer 21

anterior and posterior fontanelles and the parietal eminences

Question 22

A non-sexually active woman presents with a vaginal discharge which contains bubbles and has an offensive smell.

What is the most likely infection?

Answer 22

bacterial vaginosis

Question 23

What proportion of women with abnormal uterine bleeding will be caused by dysfunctional uterine bleeding?

Answer 23

50%

Question 24

Changes in the Endometrium in the luteal phase are direct effect of which hormone?

Answer 24

progesterone

Question 25

How long does the luteal phase last in the menstrual cycle?

Answer 25

14 days

Question 26

What information is not required when submitting an endometrial biopsy for examination?

Answer 26

number of pregnancies

Question 27

Following a dilation and curettage for a missed miscarriage the pathology report states that this is a “complete hydatidiform mole” (CHM).

What is this at higher risk of turning in to, when compared with partial moles?

Answer 27

choriocarcinoma