FORMATION OF URINE

Question 1

In the formation of urine, what happens in the proximal tubule?

Answer 1

Reabsorption of filtrate

Secretion into tubule

Question 2

In the formation of urine, what happens in the Glomerulus?

Answer 2

Filtration of blood

Question 3

In the formation of urine, what happens in the Loop of Henle

Answer 3

Concentration of urine

Question 4

In the formation of urine, what happens in the Distal tubule

Answer 4

Modification of urine

Question 5

In the formation of urine, what happens in the collecting duct

Answer 5

Final modification of urine

Question 6

what is the net filtration pressure in the glomerulus and how is this calculated?

Answer 6

Pressure within glomerular capillary PGC - Plasma protein pressure GC ( 45mmHg - 25mmHg = 10mmHg)

Question 7

What are the pressures involved in glomerular filtration

Answer 7

PGC = Pressure within glomerular capillary (hydrostatic)

GC = Plasma protein pressure (osmotic)

PBC = Pressure within Bowman’s capsule (Hydrostatic)

Question 8

Autoregulation of renal blood flow (RBF) Persists in denervated kidneys and isolated perfused kidneys - what type of response is this, neuro, hormonal or local effect

Answer 8

is NOT a neuronal or hormonal response but a local effect

Question 9

RBF subject to autoregulation over wide systemic BP range. what is the approx BP range?

Answer 9

90-200 mmHg