Foresight Flashcards

1
Q

True or False : In general, a woman who is a carrier of an X-linked condition has a 50% chance to pass that disorder on to each of her sons.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

True or False : Most of the conditions on the Foresight Carrier Screen are autosomal dominant disorders.

A

False

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

True or False : One of the many reasons that expanded carrier screening makes sense today is that the population of multi-racial Americans is growing 3x faster than the population as a whole.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

True or False : 80% of the children born with a genetic disease have no family history of that condition.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

True or False : ACOG guidelines now state that screening for cystic fibrosis and fragile X syndrome are recommended to be offered for all patients.

A

False

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

True or False : ACOG has outlined suggested disease inclusion criteria which aligns with our panel design.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

True or False : Disease selection criteria for the Foresight Carrier Screen include severity, actionability, prevalence, and sensitivity.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

True or False : All diseases on the Foresight Carrier Screen are associated with shortened life expectancy.

A

False

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

T/F

Maximizing the detection of at-risk couples is the top priority for carrier screening

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

T/F The Foresight Carrier Screen provides >99% detection for carriers of cystic fibrosis.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

True or False : The Foresight Carrier Screen includes custom assays for difficult to sequence genes.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

T/F

Fragile X and spinal muscular atrophy are examples of difficult to sequence genes on the Foresight Carrier Screen.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

True or False : Sema4, Natera, and Invitae are clinically-driven competitors.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

True or False : Convenience and ease of use are often cited by customers as reasons to select LabCorp/Integrated Genetics and Quest due to a single point of contact for all testing needs and patient service centers.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

True or False : Labs using a targeted genotyping platform report results from a select set of mutations, whereas full exon sequencing identifies all disease causing mutations within a gene.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

True or False : MWH has taken a thoughtful approach to designing Foresight, prioritizing serious, prevalent and actionable conditions.

A

True

17
Q

True or False : Sema4 and Invitae have higher at-risk couple detection rates due to their larger panel sizes.

A

False

18
Q

True or False : Foresight has an overall at-risk couple detection rate of 4.5% (1 in 22 couples) leading the industry in helping providers identify couples at-risk for serious and actionable conditions.

A

True

19
Q

True or False : Basic Carrier Screening (BCS) is defined as 10 or fewer conditions on a carrier screening panel.

A

False, >15

20
Q

True or False : Expanded Carrier Screening (ECS) is defined as 10 or more conditions on a carrier screening panel.

A

False , <15

21
Q

True or False : According to ACOG, ethnic-specific, pan-ethnic, and expanded carrier screening are all acceptable strategies for pre-pregnancy and prenatal carrier screening.

A

True

22
Q

True or False : Approximately 1 in 300 pregnancies is expected to be born with a condition included on the Foresight Carrier Screen Universal panel.

A

True

23
Q

True or False : Approximately 1 in 22 couples is expected to be identified as “at risk” for one of the conditions included on the Foresight Carrier Screen.

A

True

24
Q

True or False : The three main messages you can share with your providers to instill their confidence in the Foresight Carrier Screen are PANEL WITH PURPOSE, LEADERSHIP WITH LEGACY, and COMPLETE PRACTICE SUPPORT.

A

True