Foresight Flashcards
True or False : In general, a woman who is a carrier of an X-linked condition has a 50% chance to pass that disorder on to each of her sons.
True
True or False : Most of the conditions on the Foresight Carrier Screen are autosomal dominant disorders.
False
True or False : One of the many reasons that expanded carrier screening makes sense today is that the population of multi-racial Americans is growing 3x faster than the population as a whole.
True
True or False : 80% of the children born with a genetic disease have no family history of that condition.
True
True or False : ACOG guidelines now state that screening for cystic fibrosis and fragile X syndrome are recommended to be offered for all patients.
False
True or False : ACOG has outlined suggested disease inclusion criteria which aligns with our panel design.
True
True or False : Disease selection criteria for the Foresight Carrier Screen include severity, actionability, prevalence, and sensitivity.
True
True or False : All diseases on the Foresight Carrier Screen are associated with shortened life expectancy.
False
T/F
Maximizing the detection of at-risk couples is the top priority for carrier screening
True
T/F The Foresight Carrier Screen provides >99% detection for carriers of cystic fibrosis.
True
True or False : The Foresight Carrier Screen includes custom assays for difficult to sequence genes.
True
T/F
Fragile X and spinal muscular atrophy are examples of difficult to sequence genes on the Foresight Carrier Screen.
True
True or False : Sema4, Natera, and Invitae are clinically-driven competitors.
True
True or False : Convenience and ease of use are often cited by customers as reasons to select LabCorp/Integrated Genetics and Quest due to a single point of contact for all testing needs and patient service centers.
True
True or False : Labs using a targeted genotyping platform report results from a select set of mutations, whereas full exon sequencing identifies all disease causing mutations within a gene.
True
True or False : MWH has taken a thoughtful approach to designing Foresight, prioritizing serious, prevalent and actionable conditions.
True
True or False : Sema4 and Invitae have higher at-risk couple detection rates due to their larger panel sizes.
False
True or False : Foresight has an overall at-risk couple detection rate of 4.5% (1 in 22 couples) leading the industry in helping providers identify couples at-risk for serious and actionable conditions.
True
True or False : Basic Carrier Screening (BCS) is defined as 10 or fewer conditions on a carrier screening panel.
False, >15
True or False : Expanded Carrier Screening (ECS) is defined as 10 or more conditions on a carrier screening panel.
False , <15
True or False : According to ACOG, ethnic-specific, pan-ethnic, and expanded carrier screening are all acceptable strategies for pre-pregnancy and prenatal carrier screening.
True
True or False : Approximately 1 in 300 pregnancies is expected to be born with a condition included on the Foresight Carrier Screen Universal panel.
True
True or False : Approximately 1 in 22 couples is expected to be identified as “at risk” for one of the conditions included on the Foresight Carrier Screen.
True
True or False : The three main messages you can share with your providers to instill their confidence in the Foresight Carrier Screen are PANEL WITH PURPOSE, LEADERSHIP WITH LEGACY, and COMPLETE PRACTICE SUPPORT.
True
