Foodborne Buzzwords

Question 1

Type of toxin found in Staph Poisoning

Answer 1

SEA enterotoxin

Binds neural receptors in upper GI to stimulate vomiting center

Question 2

Which bug needs TCBS to DX

Answer 2

Vibrio Cholerae

Question 3

Which bug has both heat stable and heat labile toxins

Answer 3

ETEC

Question 4

ETEC Heat Stable enterotoxin MOA

Answer 4

increase cGMP

Question 5

ETEC heat labile enterotoxin MOA

Answer 5

increase cAMP

Question 6

EPEC Pathogenesis

Answer 6

bundle forming pili–> local adherence–>actin condensation and microvillous effacement–>attachement and effacement lesions–>stumpy stool microvillous–>malabsorption

Question 7

EAEC Pathogenesis

Answer 7

Forms Biolfilm

Cytotoxin–>inflammation of microvilio–>hemorrhagic necrosis of tips–>short and round villi–> malabsorption

Question 8

Bug that produces Hemolytic Uremic Syndrome

Answer 8

EHEC

Question 9

What is HUS

Answer 9

renal failure, thrombocytopenia, hemolytic anemia

Question 10

Dx of EHEC

Answer 10

non sorbitol fermenter on McConkey

Question 11

EHEC Pathogensis/MOA

Answer 11

Shiga like toxin nicks 60s ribosome and inhibits protein synthesis

Question 12

Dx of Campylobacter

Answer 12

Skirrow/Campy Agar

Question 13

Campylobacter associated syndromes

Answer 13

HUS, Guillaine Barre, Reactive Arthritis

Question 14

Which bug needs LowID

Answer 14

Shigella Sonnei

Question 15

shigella sonnei characteristics

Answer 15

non motile, ferments glucose and NOT lactose, COLORNESS ON MCCONKEY

Question 16

male homosexuals

Answer 16

Shigella flexerni

Question 17

Which bug is colorless on McConkey and Green on HandE

Answer 17

Shigella Dysenteriae

Question 18

What will you see on colonoscopy when infected with Shigella dysenteriae

Answer 18

mucosal inflammation and erythema, edema, ulcers (that have rod shaped bacteria and inflammatory cells)

Question 19

Explosive Diarrhea

Answer 19

Vibrio Parahemolyticus

Question 20

Bug that would show flecks of blood in stool

Answer 20

yersinia enterocolitica

Question 21

yersinia enterocolitica presentation

Answer 21

terminal ileum inflammation with enlarged mesenteric LNs

Question 22

Yersinia Enterocolitica source

Answer 22

Milk/Tofu, meat

MIMICS APPENDICITIS

Question 23

MCC of nosocomial diarrhea

Answer 23

C Diff

Question 24

C Diff colonoscopic presentation

Answer 24

pseudomembranous colitis–> tenesmus, perforation, peritonitis, death

Question 25

C Diff toxins:

Answer 25

Toxin A**:Enterotoxins** chemotactic for neutrophils, in Ileum causes cytokine release, hypersecretion of fluid and necrosis toxin B: **cytotoxin**: causes depolymerization of Actin filaments and subsequent cell death

Question 26

Salmonella Typhi characteristics

Answer 26

G-, ferments glucose NOT lactose Colorless on McConkey H₂S on HE agar LOW INFECTIOUS DOSE (like Shigela Sonnei)

Question 27

Which bug causes "Rose Spots"

Answer 27

Salmonella Typhi in **actue** infection M cells of peyer's patches--\>taken up by macrophages--\>to spleen/liver/BM--\> multiply and cause Rose Spots

Question 28

Chronic Salmonella typhii

Answer 28

colonizes gallbladder and reinfects intestine "Systemic dissemination"

Question 29

Erythemous, macropapular rashes on trunk

Answer 29

Salmonella typhi

Question 30

**TURTLES**

Answer 30

Salmonella Non Typhoid

Question 31

HOT DOGS

Answer 31

Listeria Monocytogenes

Question 32

Soft Cheeses

Answer 32

Listeria Monocytogenes

Question 33

Muscle Aches

Answer 33

Listeria Monocytogenes

Question 34

Treatment in Non Typhoidal Salmonella

Answer 34

NO ABX UNLESS THE INFECTION IS DISSEMINATED

Question 35

Bug that causes septicemia in young, old or immunocompromised?

Answer 35

Salmonella non typhoidal

Question 36

Two MCC of Viral Diarrhea

Answer 36

Calcivirus and Rotavirus