FOOD RELATED GI DISORDERS Flashcards
What is IBS ?
Chronic abdominal pain and altered bowel habits in the absence of any organic cause.
What is the aetiology and pathophysiology of IBS ?
No clear aetiology or pathophysiology is known yet. The possibilities are :
– Altered gastrointestinal motility
– Visceral hypersensitivity
– Chronic inflammation
– Alterations in faecal flora
– Bacterial overgrowth
What are the three subtypes of IBS ?
- IBS-C or constipation subtype
- IBS-M or mixed subtype
- IBS - D or diarrhoeal subtype
What is the epidemiology of IBS ?
Most commonly diagnosed GI
condition and accounts for 30% gastro referral.Ireland ~ 10-20% affected in Ireland and the Dx is typically made before age 40. More than half of people with IBS are never formally diagnosed.
What are the conditions associated to IBS ?
– Fibromyalgia
– Chronic fatigue syndrome
– Gastro-oesophageal Reflux Disease
– Functional dyspepsia
– Non-cardiac chest pain
– Psychiatric disorders
What is the clinical presentation of IBS ?
Chronic abdominal pain and altered bowel habits such as Diarrhoea or constipation. Physical examination is usually normal.
What is the Rome IV Criteria for IBS Dx ?
– Recurrent abdominal pain, on average, at least one day per week in the last three months
– Associated with two or more of the following:
* Related to defecation
* Associated with a change in stool frequency
* Associated with a change in stool form (appearance)
What is the management in IBS ?
- Lifestyle and Dietary Modifications for Patients with mild to moderate symptoms.
- Lifestyle, Dietary Modifications and Drugs for patients in whom lifestyle and dietary modification failed or in patients with moderate to severe symptoms.
What are the medications in IBS ?
- Constipation: Soluble fibres, Osmotic laxatives and Linaclotide.
- Diarrhoea - loperamide
- Abdominal pain and bloating: TCA amitriptyline or SSRIs
- Cognitive behavioural therapy (CBT)
