Food Allergy and Food Intolerance Flashcards

1
Q

What is the difference between food allergy and food intolerance?

A

Food allergy involves an immune mechanism

Food intolerance does not involve an immune mechanism

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2
Q

What are the two different types of immune mechanism in allergy and what is the difference between them?

A

Either IgE mediated or non-IgE mediated

IgE mediated tends to occur early after a food challenge

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3
Q

What kind of foods do adults tend to be allergic to?

A

Fish
Shellfish
Peanuts

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4
Q

What kind of foods do children tend to be allergic to?

A

Cows milk
Egg white
Wheat
Soy

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5
Q

Name 5 conditions that can arise due to food allergy?

A
Acute hypersensitivity
Eczema and asthma
Rhinitis and asthma
Chronic uritcaria
Food sensitive enteropathy
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6
Q

Give examples of acute hypersensitivity and also examples of food which could cause this?

A

Vomiting, diarrhoea, urticaria

Strawberries, shellfish, nuts

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7
Q

Waht immune molecule mediates acute hypersensitivity and why does acute hypersensitivity rarely produce clinical problems?

A

IgE mediated

Rarely produced problems as patients have already learned to avoid certain suspect foods

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8
Q

What might inadvertant ingestion of suspected food substances which have been known to cause the patient acute hypersensitivity lead to?

A

Angioneurotic oedema

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9
Q

Which group of patients tend to suffer from eczema and asthma?

What food tends to cause it as a food allergy?

What immune molecule mediates it?

A

Young children

Eggs

IgE mediated

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10
Q

What foods tend to cause rhinitis and asthma?

What subjects tend to suffer from this?

A

Milk and chocolate

Atopic subjects

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11
Q

How can chronic urticaria be treated?

A

Treated successfully by using an exclusion diet

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12
Q

How might food sensitive enteropathy manifest itself and what immune molecule mediates it?

A

Can manifest as:

Coeliac’s disease
and
Cow’s milk enteropathy

T cell mediated

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13
Q

Give 5 common examples of food intolerance conditions?

A
Migraine
Irritable bowel syndrome
Chinese restaurant syndrome
Lactose intolerance
Phenylketonuria
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14
Q

What foods may trigger migraines?

What do these cause migraines?

What group might be particularly vulnerable to this?

A

Chocolate, cheese, alcohol

Foods are rich in certain amines, tyramine

Patients who are on monoamine oxidase inhibitors, as these prevent the breakdown of these amines

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15
Q

What causes chinese restaurant syndrome?

What are the symptoms?

A

Monosodium glutamate - used as a favour enhancer in cooking chinese food

Symptoms:
Faintness
Dizziness
Nausea
Sweating
Chest pain
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16
Q

What causes lactose intolerance symptoms?

What food is it found in?

What are the symptoms?

A

Lactose

Milk

Abdominal bloating
Diarrhoea

17
Q

What is the cause of phenylketonuria?

A

Due to lack of phenylalanine hydroxylase which is necessary for the metabolism of dietary protein