Follow-up/Toxicity

Question 1

What are the 5- and 10-yr grades 3–4 toxicity rates following definitive RT for vaginal cancer?

Answer 1

Grades 3–4 toxicity rates are 10% and 17% at 5 and 10 yrs, respectively, following RT for vaginal cancer. (Frank SJ et al., IJROBP 2005)

Question 2

What are the 4 most common grades 3–4 late effects following definitive RT for vaginal cancer?

Answer 2

Following definitive RT for vaginal cancer, proctitis (requiring transfusion), rectal fistula, SBO, and hemorrhagic cystitis are the most common grades 3–4 toxicities.

Question 3

What common late effect may limit sexual function as well as f/u for vaginal cancer?

Answer 3

Vaginal stenosis is very common following RT for vaginal cancer. All pts should use a vaginal dilator.