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Neuroimaging > fMRI > Flashcards

fMRI Flashcards

1
Q

What is fMRI not good at doing/giving??

A

Unambiguous answers
Firing rates
Receptor localisation
Is one area ‘more active’ than another
Anything that doesn’t produce a blood flow response
Inhibitory/exhibitory activity

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2
Q

What causes a darker contrast in an MRI image?

A

shorter T2*

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3
Q

What can cause a shorter T2*?

A

Metals/dental implants etc

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4
Q

What causes the overshoot and undershoot in the haemodynamic response

A

The delay in the blood vessels expanding and then them returning to normal

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5
Q

What factors affect the BOLD signal in fMRI?

A

Physiology - CBV/CBF, metabolic oxy consumption
Equipment - field strength and homogeneity
Pulse sequence - gradient vs spin echo, echo time, repeat time, flip angle, resolution

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6
Q

What kind of ‘noise’ can affect the bold signal

A

Breathing (holding breath or increased), blood pressure, head motion, cardiac cycle, caffiene

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7
Q

How can neurovascular coupling be disrupted?

A

Drugs - vasoactive drugs
Alzheimers

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Neuroimaging (11 decks)

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