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Antibiotics > Fluoroquinolones > Flashcards

Fluoroquinolones Flashcards

1
Q

Fluoroquinolones- floxacin

A

Ciprofloxacin
Levofloxacin

MOA- inhibit DNA gyrase and topoisomerase IV

Do not take with antacids

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2
Q

Uses

A

GN,
GP
ATYPICALS

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3
Q

AEs

A

GI upset
CONTRAINDICATED IN PREGNANT, NURSING, and peds under 18- damage to cartilage

QT PROLONGATION- caused by k block, can lead to Td
Tendonitis and tendon rupture in >60 and it’s on prednisone

INHIBITS P450

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4
Q

Resistance

A

Chromosome encoded mutation in DNA gyrase, plasmid mediated resistance, efflux pumps

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Antibiotics (8 decks)

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