Fluids Flashcards

1
Q

Fluid therapy

A

 Maintain body water (patient can’t drink)
 Replace body water (patient is dehydrated/bleeding)
 Maintain blood pressure (anesthesia, shock, …)
 Diuresis (toxins, overdose)
 Other
 Vehicle to deliver drugs
 Electrolyte correction
 Parenteral nutrition
 Blood or blood product transfusion

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2
Q

Per os fluid administration

A

 Drinking
 Preferred
 Largest volumes
 Closest to nature
 Limitations
 Works if mild dehydration
 Patient must be conscious
 No vomit – Will make it worse
 No diarrhea – Won’t absorb

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3
Q

Iv fluids

A

 Fastest
 Large volume
 Status of patient does not matter
 Only choice if severely dehydrated, shock
 Can use to deliver drugs, electrolytes, nutrition
 Limitations
 High cost, technical
 Hospitalized
 Requires venous access

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4
Q

Subcutaneous fluids

A

 Under the skin
 Most common in small animals –> Cats
 Volume is limited by skin physiology
 Cats have less SQ attachment so more room
 Dogs have more attachment so less room
 Practical, fast, lower cost

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5
Q

Administering SQ fluids

A

 Aseptic technique
 Alcohol swab injection port on IV bag
 Discard needles after each use
 Generally only 0.9% NaCl or lactated ringers (LRS)
 Maximum volume is 100 ml/day cat
 Give 50 ml twice; or split into 2 (or more) sites once

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6
Q

Intraosseous fluids

A

 Into the medullary canal of a long/large bone
 Tibial tuberosity, trochanteric fossa of the femur, wing of ilium, greater tubercle
 Most common in exotics and neonates
 Technical
 Requires aseptic technique due to high risk of
osteomyelitis
 Treat similar as IV administration
 Volumes, type of fluid, fluid rate
 Short term only

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7
Q

Maintenance volumes

A

 The amount of water (fluid) intake required for basic functions in a healthy individual
 Some variation depending on source of information
 Varies with
 Species
 Size of animal
 Age (pediatric require more fluid)
 Health status (cardiac and renal most important

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8
Q

Deciding rates and volumes

A

 The rate is an order by the DVM
 “Maintenance/pediatric/surgical/shock rate”
 “Replace % or mls dehydration”
 The total amount given is an order by the DVM
 Hours of therapy
 Total volume to be infused (VTBI)
 How it is administered is determined by the RVT
 Convert order to ml/h
 Convert to drip rate
 Start and stop times

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9
Q

Prescribed rate

A

Fluid administration rate ordered by the DVM
 Expressed as ml/kg/h in small animals
 Expressed as L/kg/h in large animals

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10
Q

Infusion rate

A

The rate at which fluids are administered
 Determined from prescribed rate
 Expressed as ml/h in small animals
 Expressed as L/h in large animals
 How rates are entered in the medical record

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11
Q

Drip rate

A

The rate of fluid administration expressed as drops/sec or drops/min when using a drip-set
 Specific to the size of the drip-set being used
 Must be whole drops
 Not usually entered in the medical record

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12
Q

Delivery rate

A

The number of calibrated drops of fluid that make up 1 ml of fluid
 Expressed as drops/ml
 Must be whole drops

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13
Q

Infusion time

A

The total time over which fluids are administered
 Expressed in hours

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14
Q

Volume infused

A

The total volume of fluid administered
 Expressed in mls or liters
 Infusion rate x infusion time
 Also “volume to be infused (VTBI)”, “infusion volume”

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15
Q

IV drip administration

A

 Simplest form of IV fluid administration
 Uses gravity
 Supplies
 IV fluid bag (50 ml to 1 L, select based on patient size)
 IV infusion set (primary drip set)
 Extension set (optional*)
 Sterile needle
 Fluid stand
 Tape
 Permanent marker
 Clock or watch with second hand
 IV catheter in patient

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16
Q

IV infusion set

A

 Primary drip set, drip set
 Macro (regular) size: 10, 15 or 20 drops/ml
 Micro (pediatric) size: 60 drops/ml
 Rough guideline
 Select a macro drip if >10 kg and/or >100 ml/h
 Select a micro drip is <10 kg and/or < 100 ml/h
 Easiest to count between 1 drop/sec to 1 drop/4 sec

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17
Q

Troubleshooting fluid rates

A

 Roller clamp has variable quality/accuracy
 Long-term use wears plastic so flow rates may change
 Flow rate changes with any change in vertical distance between bag and patient; and with positioning of line
 Moving patient up or down
 Moving bag up or down
 Moving patient around
 Maximum flow rate is limited by the size of the infusion set AND the gauge of the IV catheter

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18
Q

Moving a patient on IV fluids

A

 When using a drip set:
 Rate of flow is determined by difference in height between the fluid bag and the patient
 Height will change when patient is moving this will alter flow rate
 ALWAYS turn off fluids infusion when patient is being moved
 ALWAYS re-set and confirm drip rate when patient stops moving
 Moving a patient while fluids are running risks fluid overload

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19
Q

Stopping fluid infusion

A

 Moving patient (moving from induction to OR; moving from OR to recovery); OR if no extension set
 Close slide clamps at 2 sites if possible:
1. Closest to patient
2. Closest to fluid bag
 Longer periods (bathroom, walks, x-ray) where patient is stable enough to be off fluids; and where there is an extension set
 Turn off flow
 Close slide clamps
1. Closest to patient
2. Closest to connector (on both sides of the connecter)
 Extension set stays with patient
 Disconnect and cap off both ends to maintain sterility
 Wrap extension set against patient’s leg with vetwrap
 When reconnecting the IV fluids, check catheter has not clotted or displaced
 Check by flushing

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20
Q

Y-injection ports

A

 Where medication or other fluids can be injected to be infused into the patient
 Needle-ports
 Needle-free ports (clave connectors)
 ALWAYS wipe port with alcohol before each use

21
Q

IV push or bolus

A

 Giving a medication intravenously in one-shot (not over an extended period of time)
 Can inject medication into an injection port in the IV line
 Still given over 30 seconds up to 1 minute
 Dependent on volume to be given
 Decreases how quickly the drug reaches its peak concentration anywhere in the body
 This decreases risk of adverse drug effects:
 Toxicity
 Anaphylaxis
 Overdose
 Must flush line to get into patient

22
Q

Slow IV

A

 One-shot of medication given over 10 – 20 minutes
 These drugs have more toxicity so the goal is to prevent a sudden spike
 Toxic effects if given faster

23
Q

Infusion pump

A

 Aka volumetric pump
 Force fluid into the vein under pressure
 Does not depend on gravity
 Consistent, accurate
 Must enter infusion rate: ml/hr
 Range is usually 1 ml/h to 999 ml/h
 Note: takes 5 ml/h to keep vein open
 Some models have a VTBI – will turn off after desired volume infused
 Problems:
 Risk of infiltration if catheter displaces and forces fluid into tissues
 May not alarm if problems so must check regularly
 Occlusion = line is blocked or flow is blocked

24
Q

Volume controlled burette

A

 Gravity based
 Place between IV bag and patient
 Used for greater accuracy in
1. Measuring smaller volumes
2. Delivering medications
 100-150 ml chamber size
 1 ml increments
 Chamber filled to desired amount from primary bag
 Medication injected into port
 Desired rate set manually (drip chamber) or with pump
 Previous slide shows “flow-
through” set-up
 Photo on right shows proper
way to hang burette if full
VTBI is contained in burette
 Burette MUST be perpendicular
to ground

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Flow regulators
 Component that is part of an infusion set or can be added as an extension set  Provides constant infusion rate to patient  Works by controlling size of opening  5 ml/hr to 250 ml/h  Gravity sets only  No drips to count  Single use only
26
Secondary IV
 Purpose:  Increase the amount of reservoir fluids  To deliver an intermittent medication or second type of fluid  Each bag has its own drip chamber so can set independent flow rates  Second bag of fluid is placed higher than the primary bag  Higher bag will empty first, when it is done, primary bag will then flow  Requires a specific piggy-back infusion set that connects with a Y-port
27
In line filters
 Precision filters  Openings as small as 0.2 μm  Placed in-line  Depending on type of filter, can remove air, particulate matter  Blood transfusion sets have 160-270 μm filters to remove small clots and clumps due to storage
28
Syringe pump
 Purpose: To deliver small volume of fluid (placed in the syringe) at a constant rate over given period of time  Volume determined by size of syringe  Used for 1. Medications that cannot be diluted into an IV bag 2. Fluid delivery into very small patients
29
CRI
 Continuous rate infusion  Dosing regiment used to deliver a constant amount of drug per unit time  Usually ml/kg/hr; can be as little as microliters (μl) per min  Most commonly by IV infusion  Drip rate is an example  Syringe pump delivery is an example  Can also be by transdermal delivery (e.g., patches)
30
After adding drug to an IV line
 After the medication has been administered, flush the line with 3-5 ml of 0.9% saline or LRS (enough to clear the medication from the line). Give at the same rate the medication was administered.  Also need to flush a burette if using to administer a medication. Volume should be at least 2x the amount of dead space in the tubing between the burette and the patient. Give at same rate as drug was administered.
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IV fluid types
 All IV fluids are solutions consisting of solutes that are dissolved in water  Composition varies, but in general contain:  Water  One or more electrolytes  Na+, Cl-, K+, Mg+  Buffer to regulate pH  lactate, bicarbonate, gluconate, acetate, phosphate  Colloids – Large molecular weight molecules  Dextrose for nutrition
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IV fluid classifications
Based on relation to osmotic pressure  Isotonic – same osmolarity as plasma  Hypotonic – significantly less osmotic pressure than plasma  Fluid leaves veins and enters tissue  Hypertonic – significantly greater osmotic pressure than plasma  Fluid enters veins from tissue  Balanced versus unbalanced  Balanced fluids have a profile similar to extracellular fluid (ECF)  High concentration Na+, Cl- and bicarbonate  Unbalanced fluids - Profile is not similar to ECF
33
IV fluids based on functional use
 Replacement fluids  Higher levels Na+ and Cl-  Intended for replacing lost body water or short-term use  Maintenance fluids  Lower Na+ and Cl-, higher K+  Intended for long-term use  Other – flush, hypertonic saline...
34
IV fluids based on molecular weight
Crystalloid Colloid Blood and blood products
35
Crystalloids
 Most common for maintenance and surgical fluids  Physiological saline (0.9% NaCl) mostly for flushes, flushing wounds and body cavities, can be used for replacement  LRS, Normosol, Plasmalyte, physiological saline with 20 mEq KCl
36
Colloids
 Large molecular weight solutes that cannot cross out of blood vessels  Supports oncotic pressure; draws water out of interstitial space and into blood vessels  Only used if crystalloids are not sufficient to maintain BP  Fluid selection is up to the VIC; based on each patient  Must record fluid type, rate, total volume (or start and stop times), any changes in fluid rate as they occur
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Crystalloids are
 Water + small molecular weight solutes  Electrolytes  Na+, Cl-, K+, Ca+, Mg+  Very high levels of Cl- compared to plasma  Buffers  phosphate, lactate, bicarbonate, acetate, gluconate  +/- Dextrose  Molecules are small enough to pass in and out of the blood vessels  Generally used for flushing, replacement and maintenance  Often used in anesthesia patients  Unless they are anemic or have severe hypotension  5 basic types of crystalloid
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Replacement solutions
 Isotonic - Osmolarity similar to plasma  Polyionic - Contains multiple electrolytes and buffers  Balanced – Similar to ECF  Indicated for restoring hydration, correcting hypotension, replacing electrolytes  Can be used for short-term maintenance  Need to check electrolytes q24h  Reminder: high in Na+ and Cl-; low in K+  Common examples  Lactated Ringer’s Solution* (LRS)  Normosol-R (NR)  PlasmaLyte A and R* (PA and PR)  Isolyte S (IS) * LRS and PR contain calcium and cannot be administered with blood products
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Maintenance solutions
 Compared to replacement solutions:  Contain less Na+, less Cl-  Contain more K+  Contain lower concentrations of buffers  May contain dextrose  Indicated for long-term use  Unlike replacement fluids, will not cause hypernatremia and hypokalemia over time  Common examples  Normosol-M (NM)  PlasmaLyte 56 (PL56)
40
Dextrose containing solutions
 Maintenance solutions may contain dextrose  Commonly available as 5% solution (5g/100 mL)  Can also purchase as 50% w/v solution in water to add to an IV bag  Only give dextrose solutions IV  Indicated for parenteral nutrition  Hypoglycemia, neonates, diabetics, severely debilitated (cachexic)  Common examples  LRS + 5% dextrose (D5LR)  Plasma-Lyte 56 with 5% dextrose (PL56D5)
41
Normal saline
 Physiologic saline, 0.9% saline, NaCl 0.9%  Only contains sodium and chloride dissolved in water  Isotonic, buffered to physiologic pH  Indicated for  Flushing IV catheters  Flushing wounds  Bathing tissues or body cavities during surgery  Sometimes used in place of replacement solutions – may require addition of potassium
42
Hypertonic saline
 Concentrated NaCl solution – 3%, 5%, 7% and 23.4%  Injection into vein creates very large osmotic gradient  Water moves from ECF into the intravascular space  Indicated for  Severe hyponatremia  Managing severe hemorrhage or hemorrhagic shock  Fast-acting, low-volume resuscitation (hypovolemic shock)  Treating high intracranial pressure  Contraindicated in hypernatremia, severe dehydration  Seldom used
43
Colloids are
 Contain large molecular weight solutes  Usually starch molecules too big to leave the blood vessels  Molecules increase oncotic pressure in blood vessels  Draw water into vessels  Indicated for  Hypotension and large volume losses (when crystalloids are not enough)  Low total protein (TP < 35 g/L)  Examples of synthetic colloids:  Hetastarch  Dextran
44
Blood and blood products
 Includes whole blood, RBC concentrate, platelet extract, plasma  Plasma contains albumin which is considered a “natural colloid”  Indication depends on type of product being used  Hemorrhage  Anemia  Bleeding disorders  Hypoproteinemia  Very expensive, can be hard to access, risk of adverse reaction
45
Volume overload
 Aka over-hydration  Can occur from too much fluids OR too fast fluids  Giving fluids too fast prevents them from entering into the extracellular fluid volume properly  Physiological effects of volume overload  Hypertension  Very bad if pre-existing heart disease; causes heart to work harder and can cause cardiac overload  Fluids move to 3rd spaces in the body  Abdomen, pleural space, pulmonary spaces  Most common is pulmonary edema  Can also cause cerebral edema  Can dilute oxygen carrying capacity of blood
46
Signs of volume overload
 Increased lung sounds and respiratory rate  Dyspnea  Coughing and restlessness if patient is awake  Tachycardia – why?  Increased BP  Hemodilution (decrease the relative PCV)  Ocular and nasal discharge  Chemosis  Subcutaneous edema  Neurological signs Response to volume overload 1. Reduce infusion rate 2. Give diuretics * Furosemide given IV acts in 5 minutes * Causes diuresis (i.e., promotes urination)
47
Who is most at risk for volume overload
Most at risk for volume overload:  Cardiovascular patients  HCM, heart failure, mitral valve insufficiency, hypertension  Renal failure patients  Patients <5 kg  Patients that are already anemic  Can affect the oxygen carrying capacity of the blood  Patients that are hypoproteinemic  Already have lower oncotic pressure  So fluid more likely to leave the blood vessels
48
Preventing volume overload
 Know your calculations!  Use an appropriate-sized fluid bag  ex. 100 ml for cat spay  Clamp off the line when transporting patients  Check IV line and rate hourly  Caution: most drip sets will alter their rate slowly over time  Use an infusion pump  Monitor equipment  Monitor patient  Use IV fluids when monitored and SQ fluids if not monitored
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