Fluid Management Flashcards

1
Q

The most important oncotically active constituent of ECV?

If out of normal range it is going to impact interstitial fluid and third spacing

A

Albumin

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2
Q
  • Look at their feet and hands (ex: __ patient)
  • If tachycardic, give __ and see if HR decreases (patient’s HR could be elevated from anxiety)
  • If HCT gets __ lets us know our fluid volume status is off
A
  • CHF
  • 500 NS
  • hemoconcentrated
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3
Q
  • Exchange Btw Fluid Compartments:
  • Plasma communicates continually with __ via __
  • __ and __ dictate fluid movement
  • ISF and ICF
  • __ dictate fluid movement
  • Main determinant of Extracellular osmotic pressure?
  • Main determinant of Intracellular osmotic pressure?
A
ISF
capillary pores
osmotic forces and hydrostatic pressures 
osmotic forces
sodium
potassium
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4
Q

Fluid deficit = ?

A

maintenance requirement x the number of hours patient NPO

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5
Q
  • For a 3 hour case would most likely get a ?

- Monitoring __ is vital task of anesthetist.

A
  • Foley

- blood loss

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6
Q

Blood Loss:
*We can replace blood loss __ or __

~ 3:1 = 3 cc of __ per 1 cc of blood loss - do this if think patient can tolerate other fluids than blood

~Quicker to give someone blood if they have history of __ with __. Also monitor oxygen saturation.

A

*1:1 or 3:1
~Crystalloid
~CAD with open heart surgery

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7
Q

Estimated Blood Volume (EBV):
Adults: Men? Women?

Obese patients will have increased __, due to blood going to the adipose tissue. EBV and their not doing well and their Hct is dropping - may need to give blood sooner

A
Men = 75 ml/kg
Women = 65 ml/kg

circulating blood volume

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8
Q

Allowable Blood Loss - determines how much blood you can lose to reach a particular Hct. Helps design appropriate plan and time to transfuse patient.
Equation?

A

ABL = EBV x (patients Hct - allowable Hct) /

patients Hct

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9
Q

Allowable Blood Loss (ABL):
You determine how low the hematocrit can be. There is no exact number base it off of __ (Ex: heart disease don’t let get much lower than __ before transfusing).

Allowable blood loss is based on ?
When to transfuse is based on the setting you practice in and what everyone believes.

A

co-morbidities
30/29
patient’s comorbidities

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10
Q

Evaporative loss related directly to ___ and ___.

Third space loss due to ___ and ___ caused by redistribution of fluids.
-Trauma, infection, burns

A

surface area of surgical wound and duration of exposure

massive fluid shifts and intravascular volume deficit

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11
Q

Perioperative Fluid Plan:

  • 1st hour starts when ?
  • __ = only happens when the case has started and the incision has been made
  • In the first hour, no __ yet
A

you get the IV
third space loss
blood loss

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12
Q

IV Fluid Therapy - Crystalloids:

  • Hypotonic Solutions - (?) -Replaces? -Called? -Examples?
  • Hypertonic Solutions -Used for? -Examples?
A
*253
water loss
maintenance fluids
D5W
Hyponatremia and shock
D5 1/2 NS (432)
3% NS (1026)
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13
Q

IV Fluid Therapy - Crystalloids:

  • Isotonic Solutions - (?)
  • Replaces?
  • Called?
  • Examples?
A
  • 300
  • water and electrolyte loss
  • replacement fluids
  • NS or LR
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14
Q

*__ = what we usually give. Close to same osmolarity as serum, stays in intravascular compartment, thus it expands it.

*__ = draw fluid into the intravascular space from the interstitium (give this in ?)

A

*isotonic solutions
*hypertonic solutions
neuro

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15
Q

Avoid __ if giving blood, there could be some clotting.

A

crystalloid

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16
Q
  • __ = High molecular weight. Administered in a volume equivalent to volume of blood lost.
  • Half life in circulation is __ but can be __
  • Used for __ in patients with severe __
A
*Colloid Solutions
16 hours
2-3 hours
fluid resuscitation
severe intravascular fluid deficits
17
Q
  • Belly open - at risk for evaporative loss - ? fluid

- Going to the kidneys?

A
  • Interstitial fluid

- Intravascular fluid (plasma)

18
Q

Renal don’t use fluids that contain potassium, __ contains potassium

A

Lactated Ringers

18
Q
Blood Colloid Solution - Albumin:
~Obtained from ?
~Does not contain \_\_ or \_\_
~Available as \_\_ or \_\_. Common in OR?
-Contains \_\_ at 5x the normal concentration, so it can easily expand the \_\_
A
~fractionated human plasma
~coagulation factors or blood group antibodies 
~5% or 25% solution, 5% solution
-purified albumin
-plasma volume
20
Q

***Dextran:
___ used for volume expansion
-(very similar in expansion properties as __)
___ used for prevention of thrombosis
*Side effects: ?? +
___ (1:3000 patients)
___ (can happen if you exceed doses of 20 ml/kg in 24 hours)

A
Dextran 70
albumin 5%
Dextran 40
non-cardiac pulmonary edema (d/t the toxic effects on pulm capillaries) 
interference with crossmatching
anaphylactoid reaction 
platelet inhibition
21
Q
  • **Hespan:
  • As effective as albumin for __
  • __
  • __ than albumin
  • Stored in the ___ for __ and __ excreted
  • Causes? this reduces __ levels by 50% (prolonged PTT, interferes with clotting)
  • Doses > than ? can have issues with allergic rxn and bleeding
A
  • volume expansion
  • nonantigenic
  • less expensive
  • reticuloendothelial system for several hours
  • renally excreted
  • coagulopathy due to dilutional thrombocytopenia
  • factor 8
  • > 20 mL/kg
22
Q

If your patient needs ___ it is ok to a certain extent but if you continue to need ___ for intravascular volume you should give blood.
You make the decision to switch from ?

A

colloid
colloid support
colloid to blood

23
Q

1) Support urine output better?
2) Less likely to cause pulmonary edema?
3) Associated with coagulation and antigenic problems?
4) Better at restoring severe intravascular volume deficits via oncotic P?
5) Inexpensive?
6) Fluid of choice for hypoproteinemia?
7) More tissue edema occurs with?

A
1 - crystalloids
2 - crystalloids 
3 - colloids
4 - colloids
5 - crystalloids
6 - colloids 
7 - crystalloids
24
Q

Blood Products:
Risk of __ is they dilute circulating blood products (dilute Hct).
Risk of systemic ischemia is decreased by maintaining your patients
*Risk:
1:1,000,000 at risk for __
1:300,000 at risk for __

A

fluid administration
hematocrit
HIV
Hepatitis

25
Blood Colloid Solution - Albumin: - Intravascular 1/2 life of ? - Has a near normal ? - Because of its preparation it ? - It does not have RBCs (oxygen carrying capacity). Thus it can help preserve __ and __ but cannot help our saturation. - Great choice for __, or abnormal loss of proteins from __ (?)
``` 3-6 hours oncotic pressure eliminates infectious agents blood volume and BP burn patients vascular space (liver patients) ```
26
ASA Guidelines Recommendations Regarding Blood Transfusion: - A TRANSFUSION TRIGGER IS __! - Most agree that at __ or less your patient begins to need blood, but it is reserved for those that are critically ill, unless they have severe ? * **Should you transfuse your patient at 8, true or false? - Hematocrit is roughly __ hemoglobin. - No right answer for when to transfuse-indications are what the patient?
``` NOT RECOMMENDED! 8 severe cardiovascular/respiratory disease ***False 3x can tolerate ```
27
This means they donated it, but it went to lab following donation (meaning they could have messed with it). Not giving this just because they donated it, if they do not need it do not give it!! Assumed to be safer but might not always be perfect.
Autologous unit (PRBCs)
28
If patient develops temp within 6 hours of platelet transfusion, its likely patient is having ? And the __ the platelets are the more likely this can occur.
Platelet induced sepsis (1:12,000) | older
29
~This is the leading cause of death from blood transfusion? ~Of which __ is the most frequent. ~Don't use platelets unless you need them! If platelets are stored at __ they are ok for __. After this there is higher risk of infection then even at? Acceptable to be used at __, room temp - not __!! If get platelets that are 5 days old and patient starts to have a fever need to let someone know could be platelet induced sepsis.
``` Bacterial Contamination (1:2000) Contaminated Platelets room temperature 5 days 4 days 5 days 6 days!! ```