Fluid + Fluid Balance Flashcards
What does the renal system consist of?
2 kidneys
2 ureters
Urinary bladder
Urethra
What is the function of the renal system?
Production of varying quantities of urine confusing adjustable quantities of waste allows the body to regulate fluid, electrolyte and pH balances.
Kidneys maintain homeostasis.
What do the kidneys consist of?
Renal capsule Renal cortex Renal pyramids Calyces Renal pelvis Ureter
Where are the pyramids in the kidney located?
Renal medulla
What is the pathway or urine in the kidneys?
Urine drips from top of each pyramid to: calyces pelvis ureter Ureter propels urine to the bladder
What is the main function of the kidneys?
To filter blood
What is the body water content?
50-60% of total body weight
Females less than males
Decreased in elderly
Higher in babies and infants (75-80%)
What % of body water is intracellular fluid + what electrolytes does it contain?
66% of total body water
Potassium, magnesium, phosphate
What % of body water is extracellular fluid + what electrolytes does it contain?
33%
Sodium, chloride, bicarbonate
How does the cell membrane allow for the exchange of ions?
It is selectively permeable.
Some ions are pumped out of the cell (Na+)
In exchange for other ions entering the cell (K+)
This uses energy from ATP
What is external and internal fluid balance?
External - matches input with output from body
Internal - means there is the correct volume of fluids
How is fluid exchanged across membranes?
Water distributed by osmosis
This is dependent on the osmotic pressure inside and outside the cells.
What are the most numerous solutes dissolved in body fluids + how does this affect fluid balance?
Electrolytes
Fluid balance is dependent on electrolyte balance.
What is an isotonic solution?
Same pressure inside and outside the cell
= normal RBC
What is a hypotonic solution?
Outside pressure lower than inside pressure
= swollen RBC
What is a hypertonic solution?
Inside pressure lower than outside pressure
= shrunken RBC
Why is extracellular fluid osmolality important?
It determines whether cells shrink, swell or are normal.
What solutes (and concentrations of these) does extracellular fluid contain?
NA+ 140 Cl- 140 Urea 5 Glucose 5 Others 5
equals = 300 mosmol/l
What is normal saline?
An isosmotic solution.
Contains 150 NA+ and 150 Cl-, same osmolarity as ECF.
How does fluid exchange at capillary?
Electrolytes and water in ECF exchange freely across capillary wall.
This makes interstitial fluid and plasma very similar.
However plasma pressure slightly higher due to presence of albumin.
Why is the difference in osmotic pressure of the plasma and interstitial fluid helpful?
It ensures correct plasma volume and normal fluid exchange between blood and tissue.
What is fluid balance?
The same amount of fluid enters the body as leaves the body.