Fluid & Electrolytes I Flashcards
What is Fluid Volume Excess/Hypervolemia?
Too much fluid in the vascular space (veins, capillaries, arteries)
What are the causes of FVE? Also, state 3 things with a lot of sodium.
Heart Failure (HF): Heart is WEAK, Cardiac Output (DOWN), DECREASED Kidney Perfusion, Urinary Output (DOWN). The volume stays in the vascular space.
Renal Failure: Kidneys aren’t working.
Three Things with a lot of Sodium:
- Effervescent soluble medications
- Canned/processed foods
- IVF with sodium
Tell me about Hormonal Regulation of fluid volume. Start with Aldosterone.
Aldosterone (steroid, mineralocorticoid) Found in ADRENAL GLANDS (right above kidney) Normal action: When blood volume gets low (vomiting, hemorrhage, etc.) –> Aldosterone secretion increases –> RETAIN sodium/water –> blood volume goes UP.
Give me 2 diseases with TOO MUCH aldosterone.
1. Cushing’s Disease
2. Hyperaldosteronism (Conn’s Syndrome)
Give me a disease with TOO LITTLE aldosterone.
- Addison’s Disease.
Tell me about Hormonal Regulation of fluid volume. Continuing with Atrial Natriuretic Peptide. (ANP)
ANP is found in the ATRIA of the heart. Function: Works the OPPOSITE of aldosterone. So it causes EXCRETION of SODIUM and WATER.
Continuing on with Hormonal Regulation of fluid volume. What does Anti-diuretic Hormone (ADH) do? Does it make you retain or diurese? What does it make you retain or diurese?
Normally makes you RETAIN WATER.
What are your two ADH problems?
- Too Much ADH 2. Not Enough ADH
Tell me everything you know about TOO MUCH ADH.
- Retain WATER 2. Fluid Volume EXCESS 3. Syndrome of Inappropriate ADH Secretion 4. SIADH 5. Too many LETTERS, too much WATER. 6. Urine DECREASE & Concetrated 7. Blood DILUTED
Tell me everything you know about NOT ENOUGH ADH.
- Lose (diurese) WATER
- Fluid Volume DEFICIT
- Diabetes Insipidus –> SHOCK!!!
- DI - DIabetes Insipidus (has nothing to do with your blood sugar) –> DIuresis.
- Urine is DILUTED (Large amounts)
- Blood is CONCENTRATED
Concentrated makes #’s go?
Concentrated makes #’s go up.
- Urine
- Specific Gravity
- Sodium
- Hematocrit
Dilute makes #’s go?
Dilute makes the #’s go DOWN.
- Urine
- Specific Gravity
- Sodium
- Hematocrit
Where is ADH found?
ADH (Anti-diuretic Hormone) is found in the PITUITARY. (between your eyeballs)
- Give key words to make you think potential ADH problems.
- Also, what’s another name for ADH?
- And, what drug can be utilized as an ADH replacement in Diabetes Insipidus?
A. KEY WORDS
1. Craniotomy
2. Head Injury
3. Sinus surgery
4. Transsphenoidal Hypophysectomy
Trans - go all the way through
Sphenoid - Sinus
Hypophysis - Pituitary
Ectomy - taking something out
Or any condition that can lead to INCREASED ICP can lead to an ADH problem.
B. ANOTHER NAME:
Vasopressin (Pitressin)
C. DRUG utilized as ADH replacement.
Desmopressin acetate (DDAVP) Used as nasal spray.
What are signs/symptoms of fluid volume excess?
- Distended neck veins/peripheral veins: Vessels are BIG & FULL
- Peripheral edema/third spacing: Vessels can’t hold any more, so they start to LEAK OUT.
- Central Venous Pressure (CVP): Measured in Right Atrium so NUMBER goes UP.
MORE VOLUME, MORE PRESSURE!!!
- Lung sounds: WET. (Bibasilar crackles)
- Polyuria: Kidneys are trying to help you DIURESE.
- Pulse: It goes UP. Your heart only wants fluid to go FORWARD.
- If the fluid doesn’t go forward, it’s going to go BACK into the lungs. Can lead to HEART FAILURE then PULMONARY EDEMA.
- Blood pressure goes UP. MORE VOLUME, MORE PRESSURE!!!
- Weight INCREASES. Any acute gain or loss isn’t fat, it’s FLUID.