Fluid & Electrolyte Balance Flashcards
What is Osmolarity
Amount of solutes per LITRE of a solution (VOLUME)
What is Osmolality
Amount of solutes per KILOGRAM of a solution (WEIGHT)
What is Hydrostatic pressure
Ability to push a solution across a membrane
What is oncotic pressure
Ability to attract/pull a solution across a membrane
What is Tonicity
A measurement of Osmotic/Oncotic pressure
Explain uses, and con’s of CSL/Hartmanns
Restores circulating volume & electrolyte deficits
Used in Burns, Acidosis, Hypovolaemia
Readily available, low cost, buffer
X = rapid movement from intravascular space to the extravascular space
Explain uses, pros and cons of Normal Saline
Restores circulating volume and is compatible with most drugs
Readily available, safe to use, low cost
X = Can cause Hypercholoraemia acidosis with prolonged
use
Explain uses, pros and cons of 1/2 normal saline
Hypotonic solution used in DKA, Hypertonic Dehydration, Sodium Chloride depletions, Gastric fluid loss
Maintains body fluid, Establishes renal function, OK for diabetics (No glucose)
X = Can cause cardiovascular collapse, Increase ICP, Do not use in Trauma, burns or Liver Disease
Explain uses, pros and cons of D5W
Raises fluid volume and has excretory properties. Isotonic in the bag but becomes hypotonic once metabolised in the body.
No sodium, use in dehydrations, hypernatraemia
X = Can lead to hyperglycaemia or Overload. Not calorifically complete.
Explain what Packed Red Blood Cells are used for and the infusion time
Restores intravascular volume in Trauma, Surgery or Cancer patients. Replaces 02 - carrying ability of the blood in Anaemia.
Infuse over 1 to 3 hours
Explain what Platelets are used for and the infusion time
To treat haemorrhage in major trauma or surgery, clotting disorders, cancer or leukaemia patients.
Infuse over 15 to 30 minutes
Explain what Fresh Frozen Plasma is used for and the infusion time
Replaces clotting factors and other blood proteins.
Infuse over 30 minutes
What is the Pathophysiology, Signs and symptoms, and treatment of a Haemolytic Transfusion Reaction
A systemic reaction provoked by immunologic RBC incompatibility.
Can be immune or non-immune mediated
Occurs within first 24 hours of transfusion
Signs and symptoms = Increased temp and HR, Anxiety, Flank pain, Rigors, Dyspnoea, Pain at IV site.
Treatment = Stop the transfusion Check and monitor Vital signs Maintain IV access without flushing existing line (use new if required) Check pack, documentation and patient ID Notify MO and transfusion provider
What is Preload and the factors which influence it
The amount of myocardial stretch prior to contraction. Influenced by anything that affects Ventricular volume at the end of diastole.
- Circulating Volume
- Contractility of Myocardium
- Heart rate
- Atrial contraction
- Systemic and Pulmonary pressures
What is Afterload and the factor which influence it
The amount of resistance the heart must overcome to open the Aortic valve and propel blood into systemic circulation.
- Peripheral Vascular resistance (Vessel length, diameter, and blood viscosity)
- Contractility of the Myocardium
- Volume of Blood in Ventricle (LVEDV)
What are the 4 main forces that determine fluid movement in the capillaries and interstitial space
Capillary Hydrostatic pressure - (BP) forces out of capillary to interstitium
Capillary Oncotic pressure - Proteins attract fluid from interstitium to capillaries
Interstitial Hydrostatic pressure - Fluid within interstitium forces out of interstitium and into capillaries or Lymphatic vessels
Interstitial Oncotic - Proteins in interstitium attract fluid from the capillaries into the interstitial space
How does an increase in capillary hydrostatic pressure or decrease in capillary oncotic pressure lead to oedema
Fluid balance relies on constant pressures.
Abnormal increases in capillary hydrostatic pressure forces excess fluid into the interstitial space. Abnormal decrease in capillary oncotic pressure reduces the ability of fluid to be drawn back into the capillaries
What is ment by fluid being in the third space
Fluid that accumulates outside a normal fluid compartment
What are the different body fluid compartments
Intracellular compartment - Fluid within the cells
Extracellular compartment - All fluid outside the cells
- —>Interstitial compartment - The space between cells and outside blood vessels
- —> Intravascular - Plasma
How are Sodium, Chloride and Potassium normally kept in balance
The kidneys reabsorb Sodium which forces the active transport of Chloride also.
Potassium is secreted into filtrate and excreted via the urine, and sweat