Fluid, Electrolyte, & Acid-Base Regulation (Page 1 🥲) Flashcards
Minerals in the body that are able to conduct electrical charges =
Electrolytes
Are electrolytes essential to sustain life?
Yes
Electrolytes are found in-
The blood, urine, tissues, and other body fluids
Common electrolytes include-
Potassium, Sodium, Calcium, & Magnesium
How can electrolyte levels be evaluated?
By performing metabolic panels like the BMP or CMP
A blood test that gives info like electrolyte + fluid balance. Also gives info about renal function + glucose levels =
Basic Metabolism Panel (BMP)
A blood test that gives info like electrolyte + fluid balance. Also gives info about the body’s metabolism + protein & liver function =
Complete Metabolic Panel (CMP)
What tests does a BMP provide?
Blood Urea Nitrogen (BUN), Carbon Dioxide (C02), Creatinine (CR), Glucose, Chloride (Cl- ), Potassium (K+), and Calcium (Ca+) tests
What tests does a CMP provide?
All of the tests a BMP provides, also provides Liver Enzyme , Alkaline Phosphate (ALP), Alanine Transaminase (ALT), Aspartate Aminotransferase (AST), Bilirubin (total), Protein (total), and Albumin tests
The indication that the Blood Urea Nitrogen test looks into is-
Kidney Function
The indication that the Carbon Dioxide (C02) test looks into is-
Blood Bicarbonate Level
The indication that the Creatinine (CR) test looks into is-
Kidney Function
The indication that the Glucose test looks into is-
Blood Sugar Level
The indication that the Chloride (Cl-) test looks into is-
Blood Chloride Level
The indication that the Potassium (K+) test looks into is-
Blood Potassium Level
The indication that the Sodium (Na+) test looks into is-
Blood Sodium Level
The indication that the Calcium (Ca+) test looks into is-
Liver Function
The indication that the Liver Enzymes test looks into is-
Liver Function
The indication that the Alkaline Phosphate (ALP) test looks into is-
Liver Function
The indication that the Alanine Transaminase (ALT) test looks into is-
Liver Function
The indication that the Aspartate Aminotransferase (AST) test looks into is-
Liver Function
The indication that the Bilirubin (total) test looks into is-
Liver Function
The indication that the Protein (total) test looks into is-
Total Blood Protein
The indication that the Albumin test looks into is-
Liver Function
Electrolytes are responsible for maintaining-
The balance of water in the body
Electrolytes are responsible for balancing-
The blood pH (acid-base) level
Electrolytes are responsible for moving nutrients-
Into the cells
Electrolytes are responsible for moving wastes-
Out of the cells
Electrolytes are responsible for maintaining proper function of the body’s-
Muscles, heart, nerves, and brain
The average person’s weight consists of how much water?
One-half to two-thirds water
For males, water makes up what percentage of weight?
~60% of weight
For females, water makes up what percentage of weight?
~54 %
For babies/ children, water makes up what percentage of weight?
~70 %
A poor balance of water can lead to-
Hypovolemia, Dehydration, Tachycardia, Tachypnea, Confusion, Headache, Kidney Stones, etc.
Heart rate above expected range =
Tachycardia
Respiratory rate above expected range =
Tachypnea
Organs that filter blood + excrete waste as urine =
Kidneys
Excess water loss without a loss of sodium =
Dehydration
Decrease in blood volume due to body fluid / blood loss =
Hypovolemia
Homeostasis =
Body’s natural balance
Measurements of the solutes within a solution =
Osmolality
How does the body work to maintain homeostasis?
By keeping water + electrolytes at a constant level in the blood
How can the level of water + electrolytes in the blood be monitored?
Determining the Serum Osmolality of the blood
The most frequently used laboratory indicator of the body’s fluid status =
Serum Osmolality
Expected range of Serum Osmolality =
285 - 295 m0sm / kg
As body water decreases, what increases?
The concentration of solutes
Whenever body water decreases and the concentration of solutes increases, this leads to an increase in-
Serum Osmolality and indicates decreases in hydration
Osmolality can’t be determined using urine.
True or false?
False
Urine can be used to measure Osmolality and what else?
Renal Function + Hydration Status
The expected range for urine Osmolality is -
50 - 1,200 m0sm/kg for a random specimen
Is the body’s water located within cells or outside cells?
Both
The body has how many main fluid compartments?
3
What’s the body’s largest fluid compartment?
The Intracellular Space
The Intracellular Space holds what percentage of the body’s water?
67 %
Aside from the Intracellular Space, there is also the other two compartments, which collectively come together to create the-
Extracellular Space
The two compartments that make up the extracellular space are called the-
Interstitial Space + Intravascular Space
The Intravascular Space holds what percentage of the body’s water?
8%
The Interstitial Space holds what percentage of the body’s water?
25 %
How does the water pass through the various fluid compartments in the body?
The process of Osmosis
The movement of water from an area of higher concentration to an area of lower concentration. An example is fluid moving into or out of a cell to maintain homeostasis =
Osmosis
What can Osmoreceptors detect?
Increased Osmotic Pressure
What can Baroreceptors (aortic arch, carotid sinus) detect?
Decreased Blood Pressure
Whenever osmoreceptors detect increased osmotic pressure or baroreceptors detect decreased BP, what happens next?
The Hypothalamic Neuron sends some ADH to the kidneys + blood vessels
Where is the hypothalamic neuron located?
In the Posterior Pituitary
What does the ADH do to the kidneys?
Causes an increase in the reabsorption of water
What does the ADH do to the blood vessels?
Causes Vasoconstriction
An increased reabsorption of water + vasoconstriction =
Increased Blood Volume + Increased Blood Pressure
The narrowing (constriction) of blood vessels by small muscles in their walls =
Vasoconstriction
The most obvious homeostatic mechanism to increase / retain water is the-
Thirst Response
How does the body monitor its own water balance?
The Lamina Terminalis
The Lamina Terminalis is located where?
The edge of the Hypothalamus
How does the lamina terminalis monitor the body’s water balance?
It monitors the osmolality in the ventricles of the brain
How much of a percentage increase in serum osmolality does it take to alert the brain’s sensors to a decrease in the body’s fluid volume?
A 1% increase in serum osmolality
Whenever the neurons of the laminate terminalis need to increase the body’s supply of water, they send out signals that signify -
Thirst
Whenever the brain senses excess body water, the thirst sensation-
Stops
As serum osmolality rises, what stimulates the posterior pituitary to release ADH?
The Hypothalamus
What does ADH stand for?
Antidiuretic Hormone
ADH can also be called-
Vasopressin
What does ADH act on?
The Nephrons of the Kidneys
The collecting ducts of nephrons respond to ADH by -
Increasing water absorption + decreasing urine excretion + increasing the body’s fluid volume
How does urination help the body retain water?
Urination filters the blood, which lets the blood return to circulation (the blood holds water and electrolytes so it essentially reintroduces or “recycles” water/ electrolytes)
Certain meds, dehydration, hypovolemia, overhydration can all lead to -
Fluid + Electrolyte Imbalances
The wrong IV fluids or feedings can lead to -
Fluid + Electrolyte Imbalances
Sweating, diarrhea, and vomiting can all lead to-
Fluid + Electrolyte Imbalances
What disorders can lead to Fluid + Electrolyte Imbalances?
Heart, Kidney, or Liver Disorders
What’s the expected electrolyte value range for Potassium (K+)?
3.5 to 5 mEq/L